July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Anterior segment vasculature imaging of OCT angiography
Author Affiliations & Notes
  • Xiao Zhou
    Department of Bioengineering, University of Washington, Seattle, Washington, United States
  • Qinqin Zhang
    Department of Bioengineering, University of Washington, Seattle, Washington, United States
  • Ruikang K Wang
    Department of Bioengineering, University of Washington, Seattle, Washington, United States
  • Footnotes
    Commercial Relationships   Xiao Zhou, None; Qinqin Zhang, None; Ruikang Wang, Moptim (P), Moptim (F)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 3061. doi:
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      Xiao Zhou, Qinqin Zhang, Ruikang K Wang; Anterior segment vasculature imaging of OCT angiography. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3061.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To investigate the feasibility of vascular imaging in anterior segment using OCT angiography

Methods : The anterior segment of subjects was imaged by a commercially available SD-OCTA system (Mocean 4000, Moptim Inc, China) enabled by an anterior segment lens adapter. Complex optical-microangiography (OMAG) algorithm was used to extract vascular information from the OCT scans. Each subject underwent two scans: one at temporal region, and another at nasal region. A 3x3 mm scanning pattern was utilized with 256 A-lines in fast axis and 256 B-locations in slow axis with 4 repetitions. Manual segmentation was performed on each dataset to generate enface vascular images. Subjects were recruited and scanned at both the temporal and nasal regions to test the repeatability.

Results : 20 normal subjects were enrolled in this study with a mean age of 30± 5.6 year-old. The SD-OCT with a short-wavelength provided high-resolution structural image as well as blood flow images. The blood vessel loops have been clearly observed in all regions. In addition, our study showed a good repeatability for signal strength(coefficient of variation (CV): 0.98) and vascular assessments(CV:0.95) . A representative case is shown in Figure 1.

Conclusions : This preliminary study describes a method for acquiring OCTA images of the functional microvasculature within sclera-limbal region. This technique may be useful for the objective evaluation of anterior segment diseases that have vascular involvement.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

 

Figure 1 Anterior segment vascular imaging of a 32-year-old female. A: enface OCTA image; B: structural B-scan located at the position corresponding to the yellow dashed line in A; C: The corresponding blood flow B-scan. The image size is 3 x 3mm.

Figure 1 Anterior segment vascular imaging of a 32-year-old female. A: enface OCTA image; B: structural B-scan located at the position corresponding to the yellow dashed line in A; C: The corresponding blood flow B-scan. The image size is 3 x 3mm.

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