July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Ex vivo optical performance of two distinct aberration-neutral monofocal IOL designs
Author Affiliations & Notes
  • Michelle L Cook
    Bausch + Lomb, Irvine, California, United States
  • Andrew Pilon
    Bausch + Lomb, Irvine, California, United States
  • George Lau
    Bausch + Lomb, Irvine, California, United States
  • Valeri Kolesnitchenko
    Bausch + Lomb, Irvine, California, United States
  • Footnotes
    Commercial Relationships   Michelle Cook, Bausch + Lomb (E); Andrew Pilon, Bausch + Lomb (E); George Lau, Bausch + Lomb (E); Valeri Kolesnitchenko, Bausch + Lomb (E)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 3690. doi:
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    • Get Citation

      Michelle L Cook, Andrew Pilon, George Lau, Valeri Kolesnitchenko; Ex vivo optical performance of two distinct aberration-neutral monofocal IOL designs. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3690.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To determine the relative optical performance of two aspheric, hydrophobic acrylic monofocal intraocular lenses (IOLs) with distinct aberration-neutral optical designs using point spread function (PSF) and wavefront flatness as objective measurements of optical quality.

Methods : Optical metrology of two distinct aberration-neutral, aspheric, hydrophobic acrylic monofocal IOLs (MX60E (Bausch & Lomb), CLRST (Hoya Surgical Optics)) was performed using a wavefront sensor device (SHS Ophthalmic Optocraft GmbH) using an aberration-free, ISO model cornea at set pupil sizes (3mm, 4mm, and 5mm). Point Spread Function (PSF) images with Strehl ratios along with resultant wavefront patterns, peak to valley (PV) and root mean square (RMS) values were collected. All measurements were collected in accordance with the ISO 11979-2 guidance document.

Results : PSF data and corresponding Strehl ratios of the incident light transferred to the retinal plane via an aberration free model cornea through a 3mm, 4mm, and 5mm aperture were 97%, 93%, 70%, respectively for MX60E and 92%,76%, 38%, respectively for CLRST. Wavefront measurements with an aberration neutral ISO model cornea demonstrated a consistent maintenance of a neutral aberration profile across the three apertures tested (MX60E [3mm=0.00, 4mm=0.01, 5mm=0.02] and CLRST [3mm=0.01, 4mm=0.02, 5mm=0.04].

Conclusions : Based on the observed flatness of wavefront images and higher Strehl ratio data collected, aberration-free performance can attain similar optical outcomes and remain less impacted by pre-existing corneal aberration profile, pupil size dynamics, and extant light levels. The aberration-free designs provide a medium to attain excellent retinal image quality across a broad range of pre-existing corneal aberration profiles and lighting conditions.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

 

SA profile of different aberration-free IOLs

SA profile of different aberration-free IOLs

 

PSF of different aberration-free IOLs with various aperture sizes

PSF of different aberration-free IOLs with various aperture sizes

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