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Luis Alfonso Hernandez, Elsa Cynthia Hernández Piñamora, Enrique Garcia, Vanessa Tirado, Santiago Soberón, Ana Gonzalez-H.Leon, Yurico Lopez, Luis Daniel Garcia Arzate, Jazmin Baca Moreno, Jans Fromow-Guerra, Pablo A. Juarez, Marco Beltran, Virgilio Morales-Canton, Hugo Quiroz-Mercado; Evaluation of acquired color vision deficiency in patients with primary open angle glaucoma with Rabin Cone Contrast Test and its correlation to the nerve fiber layer thickness. Invest. Ophthalmol. Vis. Sci. 2019;60(9):6151.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate acquired color vision deficiency in patients with primary open angle glaucoma by using the Rabin cone contrast test (RCCT) and comparing it to the nerve fiber layer thickness by using optical coherence tomography Spectralis ( OCT Spectralis).
Thirty eyes of (15 patients) with primary open angle glaucoma and mean age of 67.7 (± 10.3) years were included in this study. Long (L), medium (M), and short (S) CCT scores (L CCTs, M CCTs, and S CCTs, respectively) were measured using the RCCT. Visual field examinations were performed with a Humphrey visual field analyser, as well as measurements of nerve fiber layer thickness using optical coherence tomography Spectralis ( OCT Spectralis).
L, M and S CCT scores per patient were averaged (LMSavg) and correlated with contrast sensitivity, temporal inferior (TI) and nasal inferior (NI) nerve fiber thickness. The LMSavg values of the sample showed a mean of 78.62 (± 19.01), contrast sensitivity a mean of 1.50 (± 0.26), TI a mean of 101.28 (± 40.04) and NI a mean of 100.59 (± 51.80). The Pearson correlation coefficient (PCC) between LMSavg and (contrast sensitivity, NI and TI) was calculated. PCC for LMSavg vs contrast sensitivity was 0.68 with a p of .00005, PCC for LMSavg vs TI was 0.37 with a p of 0.04, and PCC for LMSavg vs NI was -0.13 with a p of 0.50.
On the one hand, a positive correlation with a significant p was found between LMSavg and contrast sensitivity, which was expected given the functional relationship between both tests. On the other hand, no significant correlation was found between LMS and TI or NI.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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