June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Tear dynamics associated with the use of soft contact lenses with a water gradient structure
Author Affiliations & Notes
  • Hisataka Fujimoto
    Kawasaki Medical School, Kurashiki, Okayama, Japan
  • Shintaro Ochi
    Inoue Eye Clinic, Japan
  • Arisu Masuda
    Kawasaki Medical School, Kurashiki, Okayama, Japan
  • Yumi Mito
    Kawasaki Medical School, Kurashiki, Okayama, Japan
  • Yasushi Inoue
    Inoue Eye Clinic, Japan
  • Junichi Kiryu
    Kawasaki Medical School, Kurashiki, Okayama, Japan
  • Footnotes
    Commercial Relationships   Hisataka Fujimoto, Alcon (F), Kowa (F), Novartis (F), Otsuka (F), Santen (F); Shintaro Ochi, Alcon (F), Santen (F); Arisu Masuda, Alcon (F); Yumi Mito, Alcon (F); Yasushi Inoue, Alcon (F), Santen (F); Junichi Kiryu, Alcon (F), Kowa (F), Novartis (F), Otsuka (F), Santen (F)
  • Footnotes
    Support  Alcon JAPAN IIT
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 333. doi:
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    • Get Citation

      Hisataka Fujimoto, Shintaro Ochi, Arisu Masuda, Yumi Mito, Yasushi Inoue, Junichi Kiryu; Tear dynamics associated with the use of soft contact lenses with a water gradient structure. Invest. Ophthalmol. Vis. Sci. 2020;61(7):333.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : In the recent years, soft contact lenses (SCLs) made of silicon hydrogel (SH) and SCLs with improved surfaces have been developed. We investigated the tear dynamics during SCL use using a non-contact measuring device.

Methods : Thirty-six individuals who regularly used SCL and had no active ocular surface disorders other than short tear breakup time (TBUT)-type dry eye were enrolled in the study. Seventeen individuals used Dailies Total 1 (DT1, Alcon), which has SH in the central portion and a high water content structure on the front and rear surfaces. The control group consisted of 19 individuals who used the One Day Acuvue Total Eye (TE, J&J) contact lens made of SH. We measured non-invasive TBUT (NITBUT) using Keratograph 5M, breakup pattern using DR-1α, ocular surface tear film thickness, SCL thickness, and tear meniscus height (TMH) using anterior optical coherence tomography, and subjective symptoms using a questionnaire. At visit 1 (v1), measurements were performed for the bare eye and for the eye with SCL in place after 15 min. At visit 2 (v2), which was scheduled 30 ± 5 days after v1, measurements were performed after the SCL had been in place for a minimum of 5 h.

Results : There were 11 men and 25 women, and the mean age was 35.5 ± 9.6 years. In the DT1 group, TMHs were 0.26 ± 0.07 mm for the bare eye and 0.19 ± 0.07 and 0.19 ± 0.06 mm for the eyes with SCL at v1 and v2, respectively. In the TE group, TMHs were 0.25 ± 0.05 mm for the bare eye and 0.24 ± 0.06 and 0.22 ± 0.07 mm for the eyes with SCL at v1 and v2, respectively. At v1 and v2, SCL thicknesses were 105 ± 11 and 101 ± 8 μm, respectively, in the DT1 group, and 95 ± 7 and 94 ± 8 μm, respectively, in the TE group.

Conclusions : Changes in the SH surface moisture rate affect the tear dynamics during SCL use. Therefore, it is important to select an SCL that is appropriate for the user.

This is a 2020 ARVO Annual Meeting abstract.

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