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Hisataka Fujimoto, Shintaro Ochi, Arisu Masuda, Yumi Mito, Yasushi Inoue, Junichi Kiryu; Tear dynamics associated with the use of soft contact lenses with a water gradient structure. Invest. Ophthalmol. Vis. Sci. 2020;61(7):333.
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In the recent years, soft contact lenses (SCLs) made of silicon hydrogel (SH) and SCLs with improved surfaces have been developed. We investigated the tear dynamics during SCL use using a non-contact measuring device.
Thirty-six individuals who regularly used SCL and had no active ocular surface disorders other than short tear breakup time (TBUT)-type dry eye were enrolled in the study. Seventeen individuals used Dailies Total 1 (DT1, Alcon), which has SH in the central portion and a high water content structure on the front and rear surfaces. The control group consisted of 19 individuals who used the One Day Acuvue Total Eye (TE, J&J) contact lens made of SH. We measured non-invasive TBUT (NITBUT) using Keratograph 5M, breakup pattern using DR-1α, ocular surface tear film thickness, SCL thickness, and tear meniscus height (TMH) using anterior optical coherence tomography, and subjective symptoms using a questionnaire. At visit 1 (v1), measurements were performed for the bare eye and for the eye with SCL in place after 15 min. At visit 2 (v2), which was scheduled 30 ± 5 days after v1, measurements were performed after the SCL had been in place for a minimum of 5 h.
There were 11 men and 25 women, and the mean age was 35.5 ± 9.6 years. In the DT1 group, TMHs were 0.26 ± 0.07 mm for the bare eye and 0.19 ± 0.07 and 0.19 ± 0.06 mm for the eyes with SCL at v1 and v2, respectively. In the TE group, TMHs were 0.25 ± 0.05 mm for the bare eye and 0.24 ± 0.06 and 0.22 ± 0.07 mm for the eyes with SCL at v1 and v2, respectively. At v1 and v2, SCL thicknesses were 105 ± 11 and 101 ± 8 μm, respectively, in the DT1 group, and 95 ± 7 and 94 ± 8 μm, respectively, in the TE group.
Changes in the SH surface moisture rate affect the tear dynamics during SCL use. Therefore, it is important to select an SCL that is appropriate for the user.
This is a 2020 ARVO Annual Meeting abstract.
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