Abstract
Purpose :
To report our experience with amniotic membrane transplantation in the management of severe shield ulcer
Methods :
Retrospective, interventional
PARTICIPANTS:
Patient with grade 3 (plaque like lesions) shield ulcers not responding to steroid therapy with or without surgical debridement.
INTERVENTION:
Amniotic membrane transplantation with stromal side down was performed in two layers after meticulous debridement of the ulcer. Bandage contact lens was inserted.
Results :
MAIN OUTCOME MEASURES:
Healing of the ulcer with no epithelial defect.
RESULTS:
The ulcer healed with disintegration or retraction of the membrane seen within 2 weeks.
Conclusions :
Amniotic membrane transplantation in combination with debridement is an effective surgical modality in the management of severe shield ulcers.
A significant decrease in symptoms and complete re epithelialization of the corneal ulcer was observed within the first 7 days. These remained stable during a mean follow-up of 12 weeks
Patients with severe chronic allergic keratoconjunctivitis benefit from amniotic membrane implantation used as a therapeutic contact lens in the treatment of persistent corneal epithelial defects and vernal plaques unresponsive to conventional medical treatment.
This is a 2020 ARVO Annual Meeting abstract.