Investigative Ophthalmology & Visual Science Cover Image for Volume 61, Issue 7
June 2020
Volume 61, Issue 7
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ARVO Annual Meeting Abstract  |   June 2020
Estimating the Prevalence of Narrow Anterior Chamber Angles in Caucasian Populations
Author Affiliations & Notes
  • Nikhil Jain
    University College London University Hospitals NHS Foundation Trust, London, United Kingdom
  • Rashad Zia
    East Kent University Hospitals NHS Foundation Trust, Ashford, United Kingdom
  • Footnotes
    Commercial Relationships   Nikhil Jain, None; Rashad Zia, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 46. doi:
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      Nikhil Jain, Rashad Zia; Estimating the Prevalence of Narrow Anterior Chamber Angles in Caucasian Populations. Invest. Ophthalmol. Vis. Sci. 2020;61(7):46.

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Abstract

Purpose : To estimate the prevalence of narrow anterior chamber angle conditions in a predominantly Caucasian population by studying the East Kent region of the United Kingdom.

Methods : A review was done of all patients attending a secondary care ophthalmology general clinic over a three-year period. Patients were assessed with: SD OCT, Humphrey visual field analyser, Ziess Forum and high frequency ultrasound and categorised into various narrow angle conditions. These were: primary narrow angle but non-occludable, narrow angle with raised IOP, occludable narrow angles, chronic narrow angle glaucoma, narrow Van Herrick but open angles, plateau iris configuration, plateau iris syndrome and phacomorphic narrow angle.

Results : A total of 14,520 patients, all of whom were between 40-89 years old, were referred to the clinic, of those 10,491 attended and were analysed. 674 (6.4%) of the patients had some classification of narrow angle condition. The majority of these patients were at relative low risk of pathology such as non-occludable narrow angles (359/53.3%) and narrow Van Herrick but open angles (93/13.8%). 0.55% of the total study population, or 8.8% of all the narrow angle patients, had an occludable angle with or without increased intraocular pressure or peripheral synechiae. Plateau iris pathology was seen in 68(10.1%) of patients with 18 of these having confirmed plateau iris syndrome after peripheral iridotomy. Phacomorphic pathology was confirmed in 75 (11.1%) patients

Conclusions : Narrow anterior chamber angles are present in a relatively large proportion (6.4%) of the patients, above the age of 40, attending general ophthalmology clinics in Caucasian populations. The majority of these (67%) are at low risk of developing acute or chronic angle closure glaucoma. Of those that can be considered high risk it may be beneficial to offer a prophylactic peripheral iridotomy or cataract surgery depending upon pathology identified on UBM.

This is a 2020 ARVO Annual Meeting abstract.

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