June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Axial Myopia and its Associations in a Very Old Russian Population. The Ural Very Old Study.
Author Affiliations & Notes
  • Jost Jonas
    University of Heidelberg, Mannheim, Germany
    Ufa Eye Research Institute, Ufa, Russian Federation
  • Gyulli Kazakbaeva
    Ufa Eye Research Institute, Ufa, Russian Federation
  • Ellina Rakhimova
    Ufa Eye Research Institute, Ufa, Russian Federation
  • Iulia Rusakova
    Ufa Eye Research Institute, Ufa, Russian Federation
  • Azalia Tulyakova
    Ufa Eye Research Institute, Ufa, Russian Federation
  • Albina Fahretdinova
    Ufa Eye Research Institute, Ufa, Russian Federation
  • Ainur Gizzatov
    Ufa Eye Research Institute, Ufa, Russian Federation
  • Songhomitra Panda-Jonas
    University of Heidelberg, Mannheim, Germany
  • Mukharram Bikbov
    Ufa Eye Research Institute, Ufa, Russian Federation
  • Footnotes
    Commercial Relationships   Jost Jonas, Biocompatibles UK Ltd. (Farnham, Surrey, UK) (Title: Treatment of eye diseases using encapsulated cells encoding and secreting neuroprotective factor and / or anti-angiogenic factor; Patent number: 20120263794 (P), Novartis (C), Patent application US 2019 0085065 A1„Agents for use in the therapeutic or prophylactic treatment of myopia or hyperopia (P); Gyulli Kazakbaeva, None; Ellina Rakhimova, None; Iulia Rusakova, None; Azalia Tulyakova, None; Albina Fahretdinova, None; Ainur Gizzatov, None; Songhomitra Panda-Jonas, Europäische Patentanmeldung 16 720 043.5 „Agents for use in the therapeutic or prophylactic treatment of myopia or hyperopia). (P), Patent holder with Biocompatibles UK Ltd. (Franham, Surrey, UK) (Title: Treatment of eye diseases using encapsulated cells encoding and secreting neuroprotective factor and / or anti-angiogenic factor; Patent number: 20120263794), (P); Mukharram Bikbov, None
  • Footnotes
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Investigative Ophthalmology & Visual Science June 2020, Vol.61, 78. doi:
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      Jost Jonas, Gyulli Kazakbaeva, Ellina Rakhimova, Iulia Rusakova, Azalia Tulyakova, Albina Fahretdinova, Ainur Gizzatov, Songhomitra Panda-Jonas, Mukharram Bikbov; Axial Myopia and its Associations in a Very Old Russian Population. The Ural Very Old Study.. Invest. Ophthalmol. Vis. Sci. 2020;61(7):78.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess the distribution of axial myopia and its associated factors in a very old Russian population.

Methods : The population-based Ural Very Old Study (UVOS) was performed in the city of Ufa/Russia with the inclusion criterion of living in the study region and having an age of 85+ years.

Results : The study included 810 individuals (595 (73.5%) women) with a mean age of 88.1 ± 2.7 years (median: 87 years; range: 85 to 97 years). Measurements of axial length (AL) were available for 671 individuals (492 (73.3%) women) (mean age: 88.0 ± 2.6 years (median: 87 years; range: 85 to 97 years). Mean AL was 23.1 ± 1.1 mm (median: 23.0mm; range: 19.5-28.8mm). Axial myopia (AL>24.50mm) and high axial myopia (AL>26.5mm) were present in 47/671 individuals (7.0%; 95% confidence interval (CI): 5.1, 8.9) and 11/671 individuals (1.6%; 95%CI: 0.7, 2.6), respectively. The prevalence of axial myopia and axial high myopia were independent of age (P=0.62 and P=0.77, resp.), gender (P=0.24 and P=0.52, resp.), region of habitation (P=0.36 and P=0.67, resp.), self-reported income (P=0.17 and P=1.00, resp.), serum concentration of glucose (P=0.75 and P=0.41, resp.), waist circumference (P=0.58 and P=0.49, resp.), systolic blood pressure (P=0.95 and P=0.21, resp.), diastolic blood pressure (P=0.18 and P=0.07, resp.), and smoking (P=0.50 and P=0.75, resp.). Prevalence of axial myopia increased with the level of education (P=0.006; regression coefficient beta: 0.11), while the prevalence of high myopia was not related (P=0.19).

Conclusions : In this very old population from Russia, the prevalence of axial myopia (7.0%; 95%CI: 5.1, 8.9) and high axial myopia (1.6%; 95%CI: 0.7, 2.6) were relatively low. High axial myopia was not related with the educational level or with self-reported income.

This is a 2020 ARVO Annual Meeting abstract.

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