Comparison of vision with multifocal contact lenses and SimVis Gekko simulations in a clinical site

Abstract

Purpose : To demonstrate that vision with multifocal contact lenses (1-Day Acuvue® Moist Multifocal) can be represented accurately with a binocular simultaneous vision simulator (SimVis Gekko)

Methods : LogMAR visual acuity (VA) at far (4m), intermediate (64cm) and near (40cm) distances, as well as through focus (TF) curves were measured in 10 subjects wearing SimVis Gekko simulating multifocal contact lenses. VA at far, intermediate and near distances was measured in another 27 patients, while wearing 1-Day Acuvue® Moist Multifocal contact lenses (M-CLs) and, in another visit, the corresponding SimVis Gekko simulation. The distance and add power of the M-CLs and the corresponding SimVis Gekko simulation were selected based upon the M-CLs fitting guide. The quality of vision of the patients in each condition was measured using the Multifocal Acceptance Score (MAS-2EV), a metric based on the perceived image quality of subjects at far and near distance, during daylight and nighttime illumination. The quality of vision was also evaluated, after the simulation or the fitting of the M-CLs, with a PRO vision questionnaire

Results : The TF curves with SimVis Gekko match those of the real M-CLs and are in good agreement with the VA measured at different distances: mean VA difference (SimVis – M-CL) 0.08±0.01, 0.12±0.01 and 0.10±0.01 logMAR VA for far, intermediate and near distances. The correlation between MAS-2EV with SimVis Gekko and with real M-CLs is highly significant for all distances, illuminations and subjects (p<0.00004). There is a statistically significant correlation between the MAS-2EV scores and the corresponding answers in PRO vision questionnaire, both for SimVis and M-CLs: p=0.009 (SimVis) and p=0.007 (M-CLs) for far distance; p=0.01 (SimVis) and p=0.006 (M-CLs) for near distance; and p=0.0004 (SimVis) and p=0.0005 (M-CLs) for night illumination. Subjects reported more fluctuations of visual quality during VA measurement with M-CLs (tear film, lens movement, pupil diameter) than with SimVis, which was deemed to be very stable

Conclusions : SimVis Gekko is a powerful tool to simulate multifocal contact lens designs, such as 1-Day ACUVUE® Moist Multifocal, and provide patients with a precise visual experience of multifocality. The MAS-2EV metric captures differences across lens designs, as well as differences across individuals in response to multifocality with SimVis Gekko

This is a 2020 ARVO Annual Meeting abstract.