June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Analysis of Color Vision Before and After Cataract Surgery Using CCT
Author Affiliations & Notes
  • Urmi Mehta
    Western University of Health Sciences, California, United States
    Gavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, Irvine, California, United States
  • ANG WEI
    Gavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, Irvine, California, United States
    Health Policy Research Institute, University of California, Irvine School of Medicine, Irvine, California, United States
  • Anna Diep
    University of California, Irvine School of Medicine, Irvine, California, United States
  • Bryan Le
    Drexel University College of Medicine, Pennsylvania, United States
  • Kevin H Nguyen
    Creighton University School of Medicine, Nebraska, United States
  • Andrew Browne
    Gavin Herbert Eye Institute, Department of Ophthalmology, Institute of Clinical and Translational Science, Department of Biomedical Engineering, University of California, Irvine, Irvine, California, United States
  • Footnotes
    Commercial Relationships   Urmi Mehta, None; ANG WEI, None; Anna Diep, None; Bryan Le, None; Kevin Nguyen, None; Andrew Browne, None
  • Footnotes
    Support  RPB unrestricted grant to UCI Department of Ophthalmology, ICTS KL2 Grant number is KL2 TR001416
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 849. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Urmi Mehta, ANG WEI, Anna Diep, Bryan Le, Kevin H Nguyen, Andrew Browne; Analysis of Color Vision Before and After Cataract Surgery Using CCT. Invest. Ophthalmol. Vis. Sci. 2020;61(7):849.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Traditional color vision tests do not consistently quantify the type and severity of acquired color vision deficiency or may be too complex for daily use. We hypothesize that cone contrast test (CCT), which overcomes these challenges, will show a difference in color contrast sensitivity before and after cataract surgery, and that this difference is correlated with changes in visual acuity (VA).

Methods : In this cohort study, 18 cataract patients in their 5th-8th decade of life scheduled for cataract surgery were enrolled (23 eyes). VA, intraocular pressure, and color vision were assessed before and after surgery. Color vision testing was performed via CCT using BCVA under photopic conditions. Average (avg) difference and SD between pre-op and post-op values for all 3 cones were calculated. A t-test comparing CCT values between groups with the best and worst VA changes and linear regression comparing the relationship between changes in VA and CCT were performed. VA was measured using Snellen VA.

Results : Avg pre-op CCT values were L-cone 52.35 (SD=40.30), M-cone 52.13 (SD=42.51), S-cone 49.52 (SD=36.19). Avg post-op CCT values were L-cone 82.30 (SD=23.52), M-cone 79.17 (26.73), S-cone 88.35 (SD=31.58). Mean differences were L-cone 29.96 (p=0.002), M-cone 27.04 (p=0.001), S-cone 38.83 (p<0.001).

Avg CCT values in the group with the greatest positive change in VA were: S-cone (avg=49.00, SD=28.69), M-cone (avg=55.67, SD=22.30), L-cone (avg=41.33, SD=30.14). Avg CCT values in the group with the least positive change in VA were: S-cone (avg=41.50, SD=29.58), M-cone (avg=35.75, SD=30.67), L-cone (avg=45.75, SD=26.70). Mean difference before and after surgery for the S-cone, M-cone, and L-cone were -7.70 (p=0.751), -19.92 (p=0.389), 4.42 (p=0.845) respectively.

Linear regression showed: L-cone [R2=0.012, B=0.005, 95% CI (-0.017, 0.027), p=0.624], M-cone [R2=0.074, B=0.015, 95% CI (-0.009, 0.040), p=0.211], S-cone [R2=0.036, B=0.010, 95% CI (-0.013, 0.033), p=0.386].

Conclusions : CCT scores significantly increased after cataract extraction for all three types of cones. The greatest difference was seen for the S-cone, indicating that blue/yellow vision is most affected by cataracts. The average difference in CCT values for all 3 cones between groups with the best and worst VA changes was insignificant. No correlation was found between VA improvement and improvement in CCT values.Changes in CCT values were independent of VA changes.

This is a 2020 ARVO Annual Meeting abstract.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×