June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Comparative analysis of choroidal structure from first trimester to third trimester pregnant women
Author Affiliations & Notes
  • Kosei Babaguchi
    Ophthalmology, The University of Tokyo, Toshima-ku, Japan
  • Keiko Azuma
    Ophthalmology, The University of Tokyo, Toshima-ku, Japan
  • Ryo Terao
    Ophthalmology, The University of Tokyo, Toshima-ku, Japan
  • Youhei Hashimoto
    Ophthalmology, The University of Tokyo, Toshima-ku, Japan
  • Kunihiro Azuma
    Ophthalmology, The University of Tokyo, Toshima-ku, Japan
  • Kohei Ueda
    Ophthalmology, The University of Tokyo, Toshima-ku, Japan
  • Tatsuya Inoue
    Ophthalmology, The University of Tokyo, Toshima-ku, Japan
  • Ryo Obata
    Ophthalmology, The University of Tokyo, Toshima-ku, Japan
  • Footnotes
    Commercial Relationships   Kosei Babaguchi, None; Keiko Azuma, None; Ryo Terao, None; Youhei Hashimoto, None; Kunihiro Azuma, None; Kohei Ueda, None; Tatsuya Inoue, None; Ryo Obata, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 1069. doi:
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      Kosei Babaguchi, Keiko Azuma, Ryo Terao, Youhei Hashimoto, Kunihiro Azuma, Kohei Ueda, Tatsuya Inoue, Ryo Obata; Comparative analysis of choroidal structure from first trimester to third trimester pregnant women. Invest. Ophthalmol. Vis. Sci. 2020;61(7):1069.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate choroidal thickness or choroidal structure of pregnant women from first trimester to third trimester using optical coherence tomography (OCT).

Methods : This prospective study included 28 eyes of 14 healthy pregnant women. Central choroidal thickness was measured using enhanced depth imaging OCT (EDI-OCT). The ratio of the luminal area to the stromal area was also assessed using binarization of the images obtained by EDI-OCT. The association of CCT with age, central retinal thickness (CRT), axial length (AL), or refractive error (RE) were analyzed.

Results : The mean CCT was 276±91μm, 304±98μm and 293±90μm at first, second and third trimester of pregnant women, respectively. The mean CCT significantly increased from first trimester to second and third trimester of pregnancy (P<.0001 and P<.0001). The mean ratio of choroidal luminal area was similar at first, second and third trimester of pregnant women (64.3±2.0%, 64.2±3.3% and 64.9±3.8%, respectively). In the multivariate analysis, there was no associating factors with CCT in each pregnant stage.

Conclusions : The CCT significantly increased from first trimester to second and third trimester of pregnancy. Multiple analysis found no factors associated with CCT.

This is a 2020 ARVO Annual Meeting abstract.

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