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Randy Brafford, Christopher Lievens, Andrew David Pucker, Alanna Nattis, Gerald McGwin, Quentin Franklin, Jyoti Dubey; Use of Systane Complete over contact lenses to alleviate lens discomfort. Invest. Ophthalmol. Vis. Sci. 2020;61(7):1487.
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The purpose of this study was to test the safety and efficacy of a new artificial tear (Systane Complete) for alleviating contact lens discomfort symptoms when it is directly applied to a worn contact lens. This new artificial tear was compared to no treatment and an existing contact lens rewetting drop (Sensitive Eyes Rewetting Drops).
This was a two-week, two-visit, double-masked study that randomized subjects with existing contact lens discomfort (Contact Lens Dry Eye Questionnaire-8 scores ≥ 12) to Systane Complete, Sensitive Eyes (rewetting drop), or no treatment. Drop groups were asked to apply drops before, twice during, and after contact lens use each day. Subjects were evaluated at both visits with a battery of common dry eye disease measures.
This study recruited 73 subjects across three study sites. Subjects in the artificial tear and rewetting drop groups had significant improvements in symptoms scores at two weeks compared to no treatment and at two weeks compared to baseline (all p < 0.0495). Dry eye signs did not significantly change at two weeks compared to baseline in either group, and there were no significant difference in signs at two weeks between the two drop groups. No adverse events were reported by any subject.
This study overall found that subjects can safely and effectively apply Systane Complete directly to soft contact lenses. Application of Systane Complete or Sensitive Eyes Rewetting Drops before, during, and after contact lens use was able to significantly and safely improve contact lens comfort and dryness symptoms.
This is a 2020 ARVO Annual Meeting abstract.
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