Investigative Ophthalmology & Visual Science Cover Image for Volume 61, Issue 7
June 2020
Volume 61, Issue 7
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ARVO Annual Meeting Abstract  |   June 2020
Monocular parafoveal and perifoveal accommodation response to random defocus changes induced by a tuneable lens
Author Affiliations & Notes
  • Najnin Sharmin
    School of Physics, University College Dublin, Dublin, Ireland
  • Petros Papadogiannis
    Department of Applied Physics, KTH Royal Institute of Technology, Stockholm, Sweden
  • Dimitry Romaschenko
    Department of Applied Physics, KTH Royal Institute of Technology, Stockholm, Sweden
  • Linda Lundström
    Department of Applied Physics, KTH Royal Institute of Technology, Stockholm, Sweden
  • Brian Vohnsen
    School of Physics, University College Dublin, Dublin, Ireland
  • Footnotes
    Commercial Relationships   Najnin Sharmin, None; Petros Papadogiannis, None; Dimitry Romaschenko, None; Linda Lundström, None; Brian Vohnsen, None
  • Footnotes
    Support  European Union’s Horizon H2020 ITN MyFUN project, grant agreement no. 675137
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 1715. doi:
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      Najnin Sharmin, Petros Papadogiannis, Dimitry Romaschenko, Linda Lundström, Brian Vohnsen; Monocular parafoveal and perifoveal accommodation response to random defocus changes induced by a tuneable lens. Invest. Ophthalmol. Vis. Sci. 2020;61(7):1715.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The aim of this study is to examine the effectiveness of the accommodative response of the adult human eye when subject to either parafoveal or perifoveal stimuli. Understanding the non-foveal accommodative response is of special relevance as it provides important insight into mechanisms that are likely linked to emmetropization and equally to myopia progression.

Methods : A near-IR laser diode (850 nm) and a fast Hartmann-Shack wavefront sensor (Thorlabs) were used to capture ocular aberrations up to the 4th Zernike order at 20 Hz framerate. The natural pupil was constricted to 3 mm by a pupil-conjugated iris. Subjects viewed monocularly green annular targets with diameter corresponding to visual fields from 2° to 16° (in 2° increments) placed at 1-meter distance on a computer screen. A current-driven tuneable lens (Optotune) placed in a conjugate pupil plane generated rapid random step defocus changes every 10 sec. within the accommodation range of each subject. A total of 6 subjects (3 emmetropes and 3 myopes) in the age range of 23 – 34 years and with normal vision were measured and their accommodative response recorded while instructed to gaze towards the center of the visual target.

Results : At 2° and 4° eccentricities, all subjects could compensate the induced defocus in the range of 90% - 100%. At eccentricities of 6°, 8°, 10°, and 12° the accommodative response reduced gradually from 70% to 15%. Beyond 14° eccentricity the accommodative response was essentially absent. Also, the accommodative response time increased with eccentricity to beyond 1 sec at 10°.

Conclusions : The findings show that the young adult eye can accommodate and de-accommodate with parafoveal and perifoveal vision although with reduced efficiency. The accommodative response gradually diminished with eccentricity and was largely absent beyond 14° eccentricity. No significant differences were found in the accommodative response between emmetropes and myopes.

This is a 2020 ARVO Annual Meeting abstract.

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