June 2020
Volume 61, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2020
Utility of ERG examination for uveitis requiring surgical treatment
Author Affiliations & Notes
  • Kazuichi Maruyama
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, OSAKA, Japan
  • Noriyasu Hashida
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, OSAKA, Japan
  • Takeshi Soma
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, OSAKA, Japan
  • Susumu Sakimoto
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, OSAKA, Japan
  • Hirokazu Sakaguchi
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, OSAKA, Japan
  • Kohji Nishida
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, OSAKA, Japan
  • Footnotes
    Commercial Relationships   Kazuichi Maruyama, SEED (F); Noriyasu Hashida, Otsuka Pharmaceutical Co., Ltd. (F); Takeshi Soma, None; Susumu Sakimoto, None; Hirokazu Sakaguchi, Menicon Co., Ltd. (F); Kohji Nishida, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 2091. doi:
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    • Get Citation

      Kazuichi Maruyama, Noriyasu Hashida, Takeshi Soma, Susumu Sakimoto, Hirokazu Sakaguchi, Kohji Nishida; Utility of ERG examination for uveitis requiring surgical treatment. Invest. Ophthalmol. Vis. Sci. 2020;61(7):2091.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : In uveitis, vitreous opacity causes decreased intraocular transparency, obscuring changes in the fundus. Moreover, severe inflammation can affect retinal function. Therefore, in cases with severe inflammation, prompt surgical intervention is very important, because visual impairment may become more severe if treatment is delayed. Here, we retrospectively analyzed electroretinogram (ERG) test results in uveitis that required surgical treatment and examined whether ERG was a useful indicator of surgical intervention.

Methods : Twenty-seven patient with uveitis were examined in this study. In a flash ERG examination, the amplitude and implicit time of the a- and b-waves were compared with the target eye. Groups that did and did not receive surgical treatment were compared with a statistical analysis.

Results : In the surgical treatment group, the a- (p<0.01) and b-wave (p<0.01) amplitudes were attenuated. Moreover, the implicit time of the a-wave was significantly later than in the non-surgical treatment group (p<0.01).

Conclusions : The amplitude of the a- and b-waves in ERG testing was attenuated in uveitis patients that underwent surgical treatment. The implicit time of the a-wave was also significantly later in that group. This suggests that the ERG test is useful as an indicator of surgical intervention.

This is a 2020 ARVO Annual Meeting abstract.

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