Persistent Retinal Detachment in Retinoblastoma: The Challenges

Abstract

Purpose : To review and describe persistent retinal detachment in eyes with retinoblastomas, its etiologies, the treatment attempts and the end result in this subgroup of patients.

Methods : An IRB approved retrospective review of patients treated for retinoblastoma with persistent retinal detachment that did not resolve after treatment. Study conducted at Miami Ocular Oncology and Retina (MOOR), Miami, Florida, USA in patient treated between 2012 and 2019.

Results : 10 eyes of 7 patients developed a persistent RD. Sex ratio F/M was 2/5. In all patients retinoblastoma and retinal detachment were present simultaneously in the first ophthalmological assessment. The mean age of diagnosis was 11 months. All eyes had advanced retinoblastoma stages. 8 eyes had local treatment with transpupillary laser, 6 eyes have received IAC, 3 patients have received systemic chemotherapy .In 9 eyes the RD had exudative and tractional components. One eye had a pure tractional RD due to persistent fetal vasculature. Only one eye had rhegmatogenous RD component with presence of a tear in addition to exudation. None of the eyes received retinal detachment surgical repair.

Conclusions : persistent retinal detachment occurs in eyes with advanced retinoblastoma stages with complex retinal detachment with more than one component. The dilemma is performing a vitrectomy in eyes with cancer and the poor visual outcome in these eyes.

This is a 2020 ARVO Annual Meeting abstract.