June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Comparison of 1 year surgical outcomes of combined cataract surgery and gonioscopy-assisted transluminal trabeculotomy (GATT) versus cataract surgery and iStent Inject
Author Affiliations & Notes
  • Hisham Hamze
    Ophthalmology , Birmingham Midland Eye Centre, City Hospital , Birmingham, United Kingdom
  • Abhijit Mohite
    Ophthalmology , Birmingham Midland Eye Centre, City Hospital , Birmingham, United Kingdom
  • Pravin Pandey
    Ophthalmology , Birmingham Midland Eye Centre, City Hospital , Birmingham, United Kingdom
  • Velota Sung
    Ophthalmology , Birmingham Midland Eye Centre, City Hospital , Birmingham, United Kingdom
  • Imran Masood
    Ophthalmology , Birmingham Midland Eye Centre, City Hospital , Birmingham, United Kingdom
  • Footnotes
    Commercial Relationships   Hisham Hamze, None; Abhijit Mohite, None; Pravin Pandey, None; Velota Sung, None; Imran Masood, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 3157. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Hisham Hamze, Abhijit Mohite, Pravin Pandey, Velota Sung, Imran Masood; Comparison of 1 year surgical outcomes of combined cataract surgery and gonioscopy-assisted transluminal trabeculotomy (GATT) versus cataract surgery and iStent Inject. Invest. Ophthalmol. Vis. Sci. 2020;61(7):3157.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Phacoemulsification cataract surgery (PCS) combined with minimally invasive glaucoma surgery (MIGS) has been shown to be efficacious in a number of studies, however, there is a paucity of comparative data in this area. We conducted a retrospective observational clinical study to evaluate the efficacy, safety and complication rates of PCS when combined with either gonioscopy-assisted transluminal trabeculotomy (GATT) or iStent Inject.

Methods : This retrospective study compared the outcomes of 37 patients who underwent combined GATT and PCS with 30 patients who underwent combined iStent Inject insertion and PCS. Patients with a variety of glaucoma diagnoses were enrolled. Cases undergoing other intraocular procedures in the same session were excluded. The primary outcome measures were intraocular pressure (IOP), number of glaucoma medications (NGM) and the secondary outcome measures were visual acuity (VA) and complications. Success was defined as IOP<21 mmHg and ≥20% reduction in IOP at 1 year regardless of the NGM. All patients had at least 1 year of follow-up. SPSS version 23.0 was used to perform paired t-test, Mann-Whitney U test and Kaplan-Meier analysis.

Results : The mean age and pre-operative IOP in the phaco-GATT and phaco-iStent groups were 74.1 ± 13 years and 70.5 ± 13.7 years, and 25.7 ± 9.3 and 18.2 ± 5.8 respectively, with only the latter being statistically significant (P<0.05). In both groups, there was a significant increase in VA and reduction in the IOP and NGM observed post-surgery (P<0.05). At one year, the phaco-GATT group achieved a significantly greater mean IOP reduction of 40.2% (11.4 ± 9.1mmHg) compared to 14.9% (3.3 ± 4.5mmHg) in the phaco iStent group (P<0.01) and a greater mean NGM reduction of 2.3 ± 1.3 in the phaco-GATT group compared to 1.1 ± 1.1 in the phaco-iStent group (P<0.01).
Three patients (8.1%) in the phaco-iStent group required further surgery to reduce the IOP compared to none in the phaco-GATT group. One patient (3.3%) in the phaco-GATT group required anterior chamber washout due to fibrinous uveitis.
At 1 year, the success rate was 35.1% in the phaco-iStent group compared to 93.3% in the phaco-GATT group.

Conclusions : GATT combined with PCS provides a greater reduction in IOP and NGM than combined iStent Inject and PCS. At 1 year, phaco-GATT group was significantly more successful.

This is a 2020 ARVO Annual Meeting abstract.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×