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Ge WANG, Xiaoyan Peng; The Imaging features of SS-OCT in Posterior Scleritis and Its Application to Clinic. Invest. Ophthalmol. Vis. Sci. 2020;61(7):3229.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the imaging features of Swept-Source Optical Coherence Tomography(SS-OCT) in different phases of posterior scleritis.
This study enrolled patients with newly diagnosed posterior scleritis,with or without anterior scleritis.The diagnosis of posterior scleritis depends on symptoms,abnormal signs in fundus,and T-sign in Color Doppler Imaging(CDI).With the exception of other defined diseases which might cause posterior segment pathological changes.All diagnosed patients underwent comprehensive laboratory examinations to identify etiology,clinical ocular examinations and CDI.Define the active phase, the stationary phase and recurrence.A clinical scoring system was used to determine unified treatment plan.During the follow-up,all patients had necessary lab tests,CDI,and same modes of SS-OCT examinations,including radial scans of maculae and optic discs,the combination scan of both macula and optic disc,and the automatically follow-up scanning.The SS-OCT features were analyzed and compared between different phases.The CDI findings were compared with SS-OCT at the same time.
The study included 11(18 eyes) patients with active posterior scleritis.The SS-OCT signs of punctate hyper-reflective lesions in choroid(15/18, 83.3%) ,choroid thickening(11/18,61.1%),sub-retinal fluid(6/18,33.3%),retinal folds(4/18,22.2%),macular(3/18,16.8%)&optic disc(7/18,38.9%) edema,choroidal structural changes(3/18,16.7%),and RPE wave-like changes(2/18,11.11%) could be seen in active phase.The choroidal thickness and structures changed significantly between active and stationary phase,while other signs also varied degrees of change in patients with treatment.When the patient suffered from the recurrence,the choroidal thickness raised again.On the other hand,compared with T-sign in CDI,which stayed positive through almost the whole course of disease,the changes of SS-OCT were more sensitive in reflecting the response to treatment.
In the diagnosis of posterior scleritis,the SS-OCT scans of punctate hyper-reflective lesions,choroid thickening and structural changes,sub-retinal fluid,retinal folds,macular and optic disc edema,and RPE wave-like changes may indicate active phase.These changes also differed in different stages of the disease.As SS-OCT is more sensitive to reflect the progress of disease than CDI, it may be helpful in monitoring disease progression and treatment outcomes.
This is a 2020 ARVO Annual Meeting abstract.
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