June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Characterizing how Racial and Socioeconomic Factors Affect Anti-VEGF Treatment Utilization and Outcomes for Diabetic Macular Edema
Author Affiliations & Notes
  • Nisha Aparna Malhotra
    Case Western Reserve University, Cleveland, Ohio, United States
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States
  • Grant L Hom
    Case Western Reserve University, Cleveland, Ohio, United States
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States
  • Thais Conti
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States
    Center for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic Foundation, Ohio, United States
  • Tyler E Greenlee
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States
    Center for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic Foundation, Ohio, United States
  • Rishi P Singh
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States
    Center for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic Foundation, Ohio, United States
  • Footnotes
    Commercial Relationships   Nisha Malhotra, None; Grant Hom, None; Thais Conti, None; Tyler Greenlee, None; Rishi Singh, Alcon/Novartis (I), Apellis (F), Bausch+Lomb (I), Genentech/Roche (I), Graybug (I), Ophthea (I), Regeneron Pharmaceutigals, Inc (I), Research to Prevent Blindness (F), Zeiss (I)
  • Footnotes
    Support  Unrestricted Grant Award from Research to Prevent Blindness to the Department of Ophthalmology at Cole Eye Institute (RPB1508DM)
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 3292. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Nisha Aparna Malhotra, Grant L Hom, Thais Conti, Tyler E Greenlee, Rishi P Singh; Characterizing how Racial and Socioeconomic Factors Affect Anti-VEGF Treatment Utilization and Outcomes for Diabetic Macular Edema. Invest. Ophthalmol. Vis. Sci. 2020;61(7):3292.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Although it is clear that minorities and people of low socioeconomic status are at greater risk of developing Diabetic Macular Edema (DME), it is unclear the extent to which these high-risk groups experience a difference in follow-up treatment post-diagnosis of DME. This retrospective cohort study compares anti-vascular endothelial growth factor (anti-VEGF) injection utilization and outcomes for DME among minority groups and patients of various socioeconomic statuses.

Methods : Charts of patients seen at a single institution between April 2012 and December 2017 were collected, yielding 639 patients who were diagnosed with DME and treated with anti-VEGF injection therapy. Based on exclusion criteria, 139 patients were eliminated, leaving 500 total patients included in the analysis. The patients’ electronic medical record data was reviewed and analyzed based on race, zip code, and insurance status to determine differences in anti-VEGF treatment utilization and outcome. The primary outcome measure is the number of anti-VEGF injections.

Results : Baseline VA between the black and white patients with DME was not significantly different (p=0.1453), but after treatment, the white patients had better post anti-VEGF treatment VA (68.38±14.92 vs. 63.78±17.65; p=0.0136). The white patients on average also received a greater number of injections over a one-year period compared to the black cohort (4.93±3.14 vs 3.20±2.43; p<0.0001) and had fewer no-show appointments (1.39±2.08 vs 3.23±3.39; p<0.0001). There is also a correlation between living in communities with lower average incomes and receiving fewer anti-VEGF injections (P=0.0051) and having more no-show appointments (p=0.0105).

Conclusions : While there were no baseline differences, DME treatment outcomes do differ based upon racial and socioeconomic status and may contribute to suboptimal outcomes. Factors such as no-show appointments and fewer anti-VEGF injections may underwrite these differences.

This is a 2020 ARVO Annual Meeting abstract.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×