Purchase this article with an account.
SEUNG MIN LEE, Suhwan Park; Association between Preoperative Foveal Thickness and Visual Outcome in Rhegmatogenous Retinal Detachment. Invest. Ophthalmol. Vis. Sci. 2020;61(7):3744.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Associations between Foveal thickness or outer nuclear layer and visual outcome in rhegmatogenous retinal detachment (RRD) are reported in some articles, however the value of preoperative foveal thickness did not researched. We performed a retrospective, interventional clinical study to learn about the correlation between preoperative foveal thickness and visual outcome in RRD using swept-source optical coherence tomography (OCT).
Medical records of patients who underwent RRD surgery and followed up for more than 12 months were reviewed retrospectively. RRD with complication except stage 1 epiretinal membrane (ERM) or other disease were excluded. In case of postoperative recurrence, macular hole and more than stage 2 ERM were also excluded. The preoperative foveal thickness was measured from outer plexiform layer (OPL) to inner segment (IS) of photoreceptor at the thinnest point of fovea in cube scan image of OCT. Preoperative foveal thickness (Pre-OPL-IS length) of both eyes and fovea attachment state were assessed and the postoperative best corrected visual acuity (BCVA) in baseline, 3, 6, 12 months was assessed. According to fovea attachment state, patients were divided to fovea-on and fovea-off group.
The fovea-on and the fovea-off group include 40 and 39 patients. Compared to the fovea-on group, BCVA at baseline, 6, 12 month and Pre-OPL-IS length decreased in the fovea-off group (p < 0.001, 0.04, 0.04, < 0.001, separatively). In the fovea-on group, mean Pre-OPL-IS length was 130.6 ± 11.4 μm, opposite eye was 128.6 ± 10.3 μm. Pre-OPL-IS length shows no correlation with BCVA and no difference between operated eye and opposite eye. In the fovea-off group, mean Pre-OPL-IS length length was 88.2 ± 26.1 μm, opposite eye was 135.1 ± 13.6 μm and BCVA was 1.18 ± 0.97 and 0.14 ± 0.19 at baseline and 12 months. Pre-OPL-IS length correlated with BCVA at baseline, 3,6,12 months and reduced comparing to opposite eye’s (p < 0.001, r = -0.614, -0.604, -0.700 and -0.662, seperatively). The ROC curve of Pre-OPL-IS length for visual acuity 20/32 determined that the cut-off value was 70 μm (AUROC = 0.956, CI, 0.896–1.000; p < 0.001, sensitivity, 0.923; specificity, 0.889).
In fovea-off RRD, preoperative foveal thickness was correlated with postoperative visual acuity and can be helpful for the prediction of visual outcome.
This is a 2020 ARVO Annual Meeting abstract.
This PDF is available to Subscribers Only