Abstract
Purpose :
To investigate the frequency of eyedrop instillation failure and its related physical and visual factors among glaucoma patients using by themselves for more than six months.
Methods :
Subjects satisfying the following conditions were enrolled: no physical disorders; visual acuity of 20/200 or more, and no conditions possibly disturbing eyedrop instillation. Patients were instructed to instill one drop of 0.1% hyaluronic acid solution while sitting into the conjunctival sac of both eyes. Subjects were analyzed for instillation failure in one eye. To investigate instillation-failure-related factors, the following were investigated: age, visual functions, head-bending angle during, maximal head-bending angle, pinching strength, physical ataxia; motor dysfunction of upper limbs; and quality of vision evaluated using the National Eye Institute Visual Function Questionnaire 25 (NEI-VFQ-25).
Results :
There were 103 investigated subjects, aged 69.15±8.73 years. The rate of instillation failure was 61.2%. The most frequent reason for instillation failure was other than the eye surface. Univariate and multiple logistic analysis revealed that advanced age, shallow head-bending angle, weaker pinching strength, worse motor dysfunction of upper limbs, physical ataxia, quality of vision, poor best-corrected visual acuity, and visual field score were risk factors of instillation failure were. The quality of vision showed a significant correlation with physical dysfunction.
Conclusions :
Instillation failure among patients using is routinely high, and some visual and physical functions are significantly related. It is highly recommended to investigate instillation failure and choose correct therapies in a patient-based fashion.
This is a 2020 ARVO Annual Meeting abstract.