Investigative Ophthalmology & Visual Science Cover Image for Volume 61, Issue 7
June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Mapping stereopsis in individuals with central field loss
Author Affiliations & Notes
  • Saeideh Ghahghaei
    The Smith-Kettlewell Eye Research Institute, San Francisco, California, United States
  • Preeti Verghese
    The Smith-Kettlewell Eye Research Institute, San Francisco, California, United States
  • Footnotes
    Commercial Relationships   Saeideh Ghahghaei, None; Preeti Verghese, None
  • Footnotes
    Support  This work was supported by National Institutes of Health R01 EY027390 to PV
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 4326. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Saeideh Ghahghaei, Preeti Verghese; Mapping stereopsis in individuals with central field loss. Invest. Ophthalmol. Vis. Sci. 2020;61(7):4326.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Central field loss (CFL) affects stereopsis in individuals with macular degeneration (MD). This is specifically true for fine stereopsis. Nevertheless, peripheral vision is usually preserved and can support coarse stereopsis, which is helpful for tasks of daily living. Awareness of which parts of the visual field support stereopsis in CFL can help with individualized rehabilitation techniques to improve eye-hand coordination or navigation.

Methods : Participants with monocular (N=2) or binocular (N=5) CFL and age-matched controls (N=5) with healthy vision participated in the study. Fixation stability and perimetry data for each eye were collected via the Optos OCT/SLO. We also used the OCT to locate the foveal pit. To find the areas that have intact vision in both eyes and can support stereopsis, we used a novel technique to generate a binocular map by overlapping monocular scotoma maps aligned on the respective foveae. We then ran participants in a stereo-perimetry experiment. Targets (with or without depth information) were presented on a random dot background across the visual field (up to 25° eccentricity). The depth targets had true binocular disparity, whereas the non-depth targets were defined by monocular cues such as contrast and dot density. The target was a 1° square region at the fovea and was m-scaled with eccentricity. The depth target had 20’ crossed disparity. In each trial, the participant was asked to maintain fixation during target presentation . During the response interval, participants (i) reported the location of the target by pointing, and (ii) indicated whether it was in depth or flat. Each location was probed at least 6 times. At each location we calculated the sensitivity to depth and then combined the data across locations to generate a stereopsis map.

Results : Controls had high sensitivity to the depth target across the visual field. For individuals with macular degeneration, sensitivity was at chance in the central field but some peripheral locations showed great sensitivity to stereopsis, in line with the predictions of their binocular scotoma map.

Conclusions : Stereo perimetry reveals which areas in the visual field provide coarse stereopsis. This lays the foundation for rehabilitation techniques for tasks that benefit from stereopsis in individuals with CFL.

This is a 2020 ARVO Annual Meeting abstract.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×