Investigative Ophthalmology & Visual Science Cover Image for Volume 61, Issue 7
June 2020
Volume 61, Issue 7
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ARVO Annual Meeting Abstract  |   June 2020
Predictors of Long-Term Visual Outcome Following Retinal Hemorrhage from Abusive Head Trauma
Author Affiliations & Notes
  • Julia E Reid
    Nemours/AI duPont Hospital for Children, Wilmington, Delaware, United States
  • Hilliary Inger
    Nationwide Children's Hospital, Ohio, United States
    The Ohio State University, Ohio, United States
  • Catherine Olson Jordan
    Nationwide Children's Hospital, Ohio, United States
    The Ohio State University, Ohio, United States
  • Nishanth Uli
    The Ohio State University, Ohio, United States
  • Lauren Tomlinson
    Children's Hospital of Philadelphia, Pennsylvania, United States
  • Caroline Chung
    The University of Pennsylvania, Pennsylvania, United States
  • David L Rogers
    Nationwide Children's Hospital, Ohio, United States
    The Ohio State University, Ohio, United States
  • Jing Jin
    Nemours/AI duPont Hospital for Children, Wilmington, Delaware, United States
  • Gil Binenbaum
    Children's Hospital of Philadelphia, Pennsylvania, United States
    The University of Pennsylvania, Pennsylvania, United States
  • Footnotes
    Commercial Relationships   Julia Reid, None; Hilliary Inger, None; Catherine Jordan, None; Nishanth Uli, None; Lauren Tomlinson, None; Caroline Chung, None; David Rogers, None; Jing Jin, None; Gil Binenbaum, None
  • Footnotes
    Support  NIH grants K12 EY015398, L30 EY018451-03, 2-P30-EY01583-26, and UL1-RR-024134, and the Richard Shafritz Chair in Ophthalmology Research
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 4418. doi:
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      Julia E Reid, Hilliary Inger, Catherine Olson Jordan, Nishanth Uli, Lauren Tomlinson, Caroline Chung, David L Rogers, Jing Jin, Gil Binenbaum; Predictors of Long-Term Visual Outcome Following Retinal Hemorrhage from Abusive Head Trauma. Invest. Ophthalmol. Vis. Sci. 2020;61(7):4418.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The visual consequences following retinal hemorrhage (RH) from abusive head trauma (AHT) can take years to manifest. We sought to characterize the long-term visual outcomes and prognostic factors in these children.

Methods : Retrospective, multicenter cohort study at 3 hospitals of children with RH from AHT with one or more follow-up eye examinations. Primary outcomes were visual acuity, motility, and intraocular findings. Initial eye findings and non-ocular injuries were examined as predictive risk factors.

Results : In total, 247 children were studied. RH severity at presentation was mild/moderate (25%), severe (56%), severe with retinoschisis or retinal folds (9%), and unspecified (10%). RH severity predicted final visual acuity (better-seeing eye), macular scar, macular atrophy, and optic atrophy (p<0.001). Initial visual acuity, optic atrophy, cerebral edema, and hypoxic-ischemic injury also predicted final visual acuity (p<0.001). At latest follow-up (mean 2.7 years, range 0.1-16.7 years), ocular findings included strabismus (32%); cortical visual impairment (24%); central visual impairment classified as mild/moderate (9%), severe/near-total/total (11%), unspecified (2%); optic atrophy (12%); macular scar (7%); nystagmus (5%); macular atrophy (3%). Of 5 children with normal vision who underwent macular optical coherence tomography, 3 had abnormal findings.

Conclusions : Severity of RH and other presenting factors can provide predictive information about final visual outcomes in AHT. While visual impairment and strabismus are common in children with RH from AHT, long-term follow-up is often lacking. Permanent changes to the retina can occur without obviously impacting vision. Caregivers can be counseled and long-term clinical follow-up should be ensured to monitor for visual problems throughout childhood.

This is a 2020 ARVO Annual Meeting abstract.

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