Abstract
Purpose :
The purpose of this study was to determine whether adjustable sutures have a higher success rate than nonadjustable sutures in strabismus surgery in pediatric patients.
Methods :
A comprehensive systematic review of published and unpublished records was conducted using databases MEDLINE, EMBASE, CINAHL, and Cochrane Library. Also searched were the annual meeting databases of the Canadian Ophthalmological Society, the Association for Research in Vision and Ophthalmology, the European Society of Cataract & Refractive Surgeons, and the American Academy of Ophthalmology. Dissertations and theses were also searched on Web of Science, ProQuest, and Clinical Trials. There were no date restrictions in the search. All searches were conducted till 12 August 2019. Covidence software was used to conduct the systematic review. Quality check of the included articles was done using Downs and Black. Data was extracted from included articles. STATA 15.0 was used to do the meta-analysis.
Results :
There were 1,232 number of hits from various databases, including grey literature, and 1,095 total articles screened at 3-levels. 3 articles were included in our study. Our meta-analysis results indicated significant success in both adjustable and nonadjustable strabismus surgery. Significant success rate for primary surgery was observed with adjustable suture for exotropia (ES = 0.8; 95% CI: [0.77, 0.84]) vs nonadjustable suture for exotropia (ES = 0.66; 95% CI: [0.58, 0.74]) and with adjustable suture for esotropia (ES = 0.84; 95% CI: [0.81, 0.88]) vs nonadjustable suture for esotropia (ES = 0.72; 95% CI: [0.63, 0.81]). Additionally, significant success rate was observed for secondary surgery with adjustable suture for exotropia (ES = 0.69; 95% CI: [0.65, 0.73]) vs nonadjustable suture for exotropia (ES = 0.54; 95% CI: [0.45, 0.62]) and with adjustable suture for esotropia (ES = 0.72; 95% CI: [0.67, 0.76]) vs nonadjustable suture for esotropia (ES = 0.51; 95% CI: [0.38, 0.64]).
Conclusions :
Our study results showed significant success rate for primary as well as secondary surgery with adjustable for exotropia as esotropia patients compared to vs nonadjustable sutures. More good quality randomized controlled trials are required to make concrete conclusions.
This is a 2020 ARVO Annual Meeting abstract.