June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Retinal sensitivity and foveal fixation, measured by photopic and scotopic microperimetry, in patients with diabetic retinopathy and healthy subjects
Author Affiliations & Notes
  • Nicolás Pérez-Llombet Quintana
    OPHTHALMOLOGY, HOSPITAL DE LA CANDELARIA, Santa Cruz De Tenerife, STA CRUZ DE TFE, Spain
  • Consuelo Fernández-Núñez
    OPHTHALMOLOGY, HOSPITAL DE LA CANDELARIA, Santa Cruz De Tenerife, STA CRUZ DE TFE, Spain
  • María Alberto-Pestano
    OPHTHALMOLOGY, HOSPITAL DE LA CANDELARIA, Santa Cruz De Tenerife, STA CRUZ DE TFE, Spain
  • Oswaldo Esteban Duran Carrasco
    OPHTHALMOLOGY, HOSPITAL DE LA CANDELARIA, Santa Cruz De Tenerife, STA CRUZ DE TFE, Spain
  • Marta Alonso-Plasencia
    OPHTHALMOLOGY, HOSPITAL DE LA CANDELARIA, Santa Cruz De Tenerife, STA CRUZ DE TFE, Spain
  • María Gil-Hernández
    OPHTHALMOLOGY, HOSPITAL DE LA CANDELARIA, Santa Cruz De Tenerife, STA CRUZ DE TFE, Spain
  • Rodrigo Abreu-González
    OPHTHALMOLOGY, HOSPITAL DE LA CANDELARIA, Santa Cruz De Tenerife, STA CRUZ DE TFE, Spain
  • Footnotes
    Commercial Relationships   Nicolás Pérez-Llombet Quintana, None; Consuelo Fernández-Núñez, None; María Alberto-Pestano, None; Oswaldo Esteban Duran Carrasco, None; Marta Alonso-Plasencia, None; María Gil-Hernández, None; Rodrigo Abreu-González, None
  • Footnotes
    Support  NONE
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 4854. doi:
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      Nicolás Pérez-Llombet Quintana, Consuelo Fernández-Núñez, María Alberto-Pestano, Oswaldo Esteban Duran Carrasco, Marta Alonso-Plasencia, María Gil-Hernández, Rodrigo Abreu-González; Retinal sensitivity and foveal fixation, measured by photopic and scotopic microperimetry, in patients with diabetic retinopathy and healthy subjects. Invest. Ophthalmol. Vis. Sci. 2020;61(7):4854.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Microperimetry is currently a very useful tool for determining central vision defects produced by multiple macular conditions, such as diabetic retinopathy. Our goal is to evaluate the values of fixation and retinal sensitivity of patients with diabetic retinopathy compared to a group of healthy individuals.

Methods : Thirteen-point photopic and scotopic central microperimetry was performed using the Nidek MP3S (Hiroshi, Japan) equipment in 36 eyes of 23 patients with varying grades of diabetic retinopathy: mild (17.4%), moderate (30.4%), severe (8.7%) and proliferative (43.5%).
The same scans were performed in a group of 41 eyes of 22 healthy individuals, with corrected visual acuity of 0.00 (Log Mar) and a spherical equivalent of less than +/- 5.0. Both groups had a similar average age and gender distribution.

Results : The mean retinal sensitivity (RS) in photopic microperimetry of healthy patients was 29.49 dB (± 0.64), while in diabetic patients we obtained a 23.9 dB (± 1.56) average value; showing statistically significant results (p<0.05). In the same way for scotopic examination mode the mean RS was 14.5 dB (± 0.64) in healthy subjects’ group versus 10.56 dB (±0.96).
Referring to central retinal sensitivity, we found values for the healthy group of 29.22 dB (±0.76) and 12.28 dB (±0.8), compared with 22.98 dB (±1.62) and 7.74 dB (±1.16) in diabetic patients group for photopic and scotopic microperimetry respectively (p<0.05).
Finally, the average fixation value in the two central degrees in the group of healthy individuals was 92.17% (±4.62), versus 77.36% (±8.22) in diabetic patients (p<0.05).

Conclusions : Central retinal sensitivity in patients with diabetic retinopathy is considerably lower than healthy individuals with a statistically significant difference, and foveal fixation capacity is also diminished, so we believe that microperimetry may be useful in functional evaluation of patients with diabetic retinopathy.

This is a 2020 ARVO Annual Meeting abstract.

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