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Tarun Sharma, Liang Han, Janet R Sparrow, Tongalp H Tezel; Quantitative Fundus Autofluorescence (qAF) Indicates Two Different Phenotypes in Central Serous Chorioretinopathy (CSCR). Invest. Ophthalmol. Vis. Sci. 2020;61(7):5330.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate qAF changes in central serous chorioretinopathy (CSCR).
Fundus AF images (488-nm excitation) were acquired from 22 eyes of 15 patients with CSCR (Mean age: 51.27±10.71; 7 bilateral). qAF8 values were calculated as the mean of 8 concentric segments (qAF8) located at an eccentricity of 7-9 degree. Change in qAF were correlated with anatomical changes observed on horizontal SD-OCT scans.
In 9/22 eyes, serous detachment was involving the parapapillary area. qAF8 values were higher in eyes involving the parapapillary area compared to CSCR confined to fovea (7.88±4.38 vs. 6.72±2.37; p<0.05). Involvement of parapapillary area also resulted an increase in qAF compared to fellow eyes (436.07±203.1 versus 392.36±249.91; p=0.7). Color-coded qAF images revealed the extension of qAF alterations beyond the clinically visible borders of CSCR.
qAF reveals two different presentations of CSCR and displays the extend of the RPE pathology beyond visible borders of the clinical picture.
This is a 2020 ARVO Annual Meeting abstract.
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