June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Quantitative Fundus Autofluorescence (qAF) Indicates Two Different Phenotypes in Central Serous Chorioretinopathy (CSCR)
Author Affiliations & Notes
  • Tarun Sharma
    Ophthalmology, Columbia University, New York, New York, United States
  • Liang Han
    Ophthalmology, Columbia University, New York, New York, United States
    Ophthalmology, Peking University Third Hospital, Beijing, China
  • Janet R Sparrow
    Ophthalmology, Columbia University, New York, New York, United States
  • Tongalp H Tezel
    Ophthalmology, Columbia University, New York, New York, United States
  • Footnotes
    Commercial Relationships   Tarun Sharma, None; Liang Han, None; Janet Sparrow, None; Tongalp Tezel, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 5330. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Tarun Sharma, Liang Han, Janet R Sparrow, Tongalp H Tezel; Quantitative Fundus Autofluorescence (qAF) Indicates Two Different Phenotypes in Central Serous Chorioretinopathy (CSCR). Invest. Ophthalmol. Vis. Sci. 2020;61(7):5330.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To investigate qAF changes in central serous chorioretinopathy (CSCR).

Methods : Fundus AF images (488-nm excitation) were acquired from 22 eyes of 15 patients with CSCR (Mean age: 51.27±10.71; 7 bilateral). qAF8 values were calculated as the mean of 8 concentric segments (qAF8) located at an eccentricity of 7-9 degree. Change in qAF were correlated with anatomical changes observed on horizontal SD-OCT scans.

Results : In 9/22 eyes, serous detachment was involving the parapapillary area. qAF8 values were higher in eyes involving the parapapillary area compared to CSCR confined to fovea (7.88±4.38 vs. 6.72±2.37; p<0.05). Involvement of parapapillary area also resulted an increase in qAF compared to fellow eyes (436.07±203.1 versus 392.36±249.91; p=0.7). Color-coded qAF images revealed the extension of qAF alterations beyond the clinically visible borders of CSCR.

Conclusions : qAF reveals two different presentations of CSCR and displays the extend of the RPE pathology beyond visible borders of the clinical picture.

This is a 2020 ARVO Annual Meeting abstract.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×