Abstract
Purpose :
To evaluate long-term clinical outcomes of central serous chorioretinopathy in different fundus autofluorescence patterns
Methods :
This retrospective study included 49 eyes of 48 patients from 3 years follow-up of 126 eyes diagnosed with central serous chorioretinopathy from December 2006 to April 2012. Visual acuity, central subfield thickness, choroidal thickness, type of therapy, event of choroidal neovascularization and autofluorescene patterns were examinated.
Results :
Fundus autofluorescence patterns of 49 eyes were grouped as blocked (20, 40.8%), mottled (5, 10.2%), hyper (14, 28.6%), hyper/hypo (4, 8.2%), or descending tract (6, 12.2%), average onset age was 48.6±9. After 3 years, the mottled pattern group had the best visual acuity (p<0.05) and descending tract pattern group had the worst visual acuity (p<0.05). AF pattern progression showed total 31 of 49 eyes (63.3%), blocked (85.0%), hyper (64.3%), hyper/hypo (50.0%), descending tract (0.0%). AF pattern progression was statically correlated with duration of symptom and other factors were not statically correlated. VA after 3yrs follow-up was statically correlated with duration of symptom, VA at first visit, CST and IS/OS integrity after 3yrs follow-up.
Conclusions :
The pattern of early autofluorescence in the central serous choroidal retinopathy may be helpful in determining long-term visual outcome as well as early visual acuity. Changes seen in optical coherence tomography are also associated with visual prognosis. Therefore, early autofluorescence pattern and optical coherence tomography analysis of patients with central serous chorioretinopathy can be used to evaluate the long-term prognosis of patients.
This is a 2020 ARVO Annual Meeting abstract.