Abstract
Purpose :
To examine the predictability of medial rectus tendon thickness measured by anterior segment optical coherence tomography (AS-OCT) on corticosteroid response for vertical strabismus associated with thyroid eye disease (TED).
Methods :
Thirteen patients with TED-induced vertical strabismus who underwent intravenous methylprednisolone therapy and/or radiotherapy, or repeated peribulbar injections of triamcinolone were retrospectively analyzed. Medial rectus tendon thickness was measured using anterior segment optical coherence tomography (CASIA2®, TOMEY, NAGOYA, JAPAN) at nasal 8.7 mm from the corneal limbus. The larger value of the left and right medial rectus muscle tendon was used for analysis. Responder group was defined as disappearance of diplopia during front view or improvement of vertical deviation angle by 5°with HESS screen test at three months following induction of corticosteroid therapy.
Results :
The responder group comprised 9 patients (69%), and the non-responder group comprised 4 patients (31%). The thickness of the medial rectus tendon in the non-responder group (73±89 µm, range: 278 to 493 µm) was larger than that in the responder group (197±41 µm, range: 149-240 µm) (p=0.028, Mann-Whitney test).
Conclusions :
Medial rectus muscle tendon thickness is useful parameter for prediction of corticoid response for TED-induced vertical strabismus. Studies with larger sample size is needed in the future.
This is a 2020 ARVO Annual Meeting abstract.