June 2020
Volume 61, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2020
Evaluation of the SITA Standard 24-2C visual field test
Author Affiliations & Notes
  • Thomas Callan
    Carl Zeiss Meditec, Inc., Dublin, California, United States
  • Gary C Lee
    Carl Zeiss Meditec, Inc., Dublin, California, United States
  • Sophia Yu
    Carl Zeiss Meditec, Inc., Dublin, California, United States
  • Nolleisha Graves
    Carl Zeiss Meditec, Inc., Dublin, California, United States
  • Charles Wu
    Carl Zeiss Meditec, Inc., Dublin, California, United States
  • Mary K Durbin
    Carl Zeiss Meditec, Inc., Dublin, California, United States
  • Iryna Falkenstein
    Glaucoma Specialists of San Francisco, Oakland, California, United States
  • Todd Severin
    East Bay Eye Center, San Ramon, California, United States
  • Footnotes
    Commercial Relationships   Thomas Callan, Carl Zeiss Meditec, Inc. (E); Gary Lee, Carl Zeiss Meditec, Inc. (E); Sophia Yu, Carl Zeiss Meditec, Inc (E); Nolleisha Graves, Carl Zeiss Meditec, Inc. (C); Charles Wu, Carl Zeiss Meditec, Inc. (C); Mary Durbin, Carl Zeiss Meditec, Inc. (E); Iryna Falkenstein, Carl Zeiss Meditec, Inc. (C); Todd Severin, Carl Zeiss Meditec, Inc. (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 3876. doi:
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      Thomas Callan, Gary C Lee, Sophia Yu, Nolleisha Graves, Charles Wu, Mary K Durbin, Iryna Falkenstein, Todd Severin; Evaluation of the SITA Standard 24-2C visual field test. Invest. Ophthalmol. Vis. Sci. 2020;61(7):3876.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Some clinicians prefer to test their glaucoma patients with the SITA Standard strategy when performing visual fields. The recent SITA Faster 24-2C test for the HFA3 perimeter includes 10 points from the SITA 10-2 pattern tested at the end of the SITA Faster 24-2 threshold test. This preliminary study evaluated the central points of a new prototype SITA Standard 24-2C test.

Methods : Each normal and glaucoma subject took four tests on one eye at each of two visits with an HFA3 Model 860 perimeter (ZEISS, Dublin, CA): the prototype SITA Standard 24-2C, SITA Faster 24-2C, SITA Standard 10-2 and SITA Fast 10-2 test. Scatterplot and Bland-Altman (B-A) analysis were used to compare the mean deviation (MD) of the two 24-2C test strategies for both visits. The number of total deviation (TD) and pattern deviation (PD) points flagged for the 10 common points in the SITA Standard 24-2C and SITA Standard 10-2 tests were totaled and compared using paired equivalence t-tests (α = 0.05) for the second visit. The limits of equivalence were chosen to be +/- 2 points.

Results : Thirteen normal (mean age: 55.3 years, SD 7.7, range 44-69) and thirteen glaucoma (mean age: 70.5 years, SD 6.0, range 61-81) subjects were tested. The mean deviations (MDs) were similar between both strategies for normal and glaucoma subjects and illustrated for the glaucomas in Figure 1a & 1b. The number of flagged TD and PD P<0.05 points in the central 10 degrees between the 24-2C SITA Standard points and the SITA Standard 10-2 were statistically equivalent. For the normal group, the TD mean difference was 0.8 (SD: 0.5) points, the PD difference 0.9 (1.8) points while the glaucoma TD mean difference was 0.5 (0.9) and PD difference 0.4 (1.4) points (see Table 1).

Conclusions : The SITA Standard 24-2C test pattern showed a similar sensitivity to detect visual field loss in the new central 10-degree test locations as the SITA Standard 10-2 test. The SITA Standard 24-2C test may offer earlier detection of central visual field loss without the need to run a supplementary SITA 10-2. These results are similar to results from previous studies comparing the SITA Faster 24-2C and the SITA Fast 10-2 tests.

This is a 2020 ARVO Annual Meeting abstract.

 

Figure 1a & 1b: Linear regression and B-A plots for mean deviation (MD) of glaucoma patients (both visits)

Figure 1a & 1b: Linear regression and B-A plots for mean deviation (MD) of glaucoma patients (both visits)

 

Table 1: Mean number of flagged TD and PD points for normal and glaucoma subjects (visit two)

Table 1: Mean number of flagged TD and PD points for normal and glaucoma subjects (visit two)

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