June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Correlation between retinal sensitivity assessed by microperimetry and the full-thickness and ganglion cell complex thickness measurements after internal limiting membrane peeling in eyes with idiopathic epiretinal membrane
Author Affiliations & Notes
  • Raphael Lucas Sampaio Defina
    Federal University of Juiz de Fora , Juiz de Fora, Minas gerais, Brazil
  • Aline Mota Freitas Matos
    Federal University of Juiz de Fora , Juiz de Fora, Minas gerais, Brazil
  • Luciana Virgínia Ferreira Costa-Cunha
    Juiz de Fora Eye Hospital, Juiz de Fora, Minas Gerais, Brazil
  • Camila Borelli Zeller
    Federal University of Juiz de Fora , Juiz de Fora, Minas gerais, Brazil
  • Mario L R Monteiro
    Ophthalmology, University of São Paulo, São Paulo, São Paulo, Brazil
  • Leonardo Provetti Cunha
    Federal University of Juiz de Fora , Juiz de Fora, Minas gerais, Brazil
    Ophthalmology, University of São Paulo, São Paulo, São Paulo, Brazil
  • Footnotes
    Commercial Relationships   Raphael Defina, None; Aline Matos, None; Luciana Costa-Cunha, None; Camila Zeller, None; Mario Monteiro, None; Leonardo Cunha, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 4240. doi:
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      Raphael Lucas Sampaio Defina, Aline Mota Freitas Matos, Luciana Virgínia Ferreira Costa-Cunha, Camila Borelli Zeller, Mario L R Monteiro, Leonardo Provetti Cunha; Correlation between retinal sensitivity assessed by microperimetry and the full-thickness and ganglion cell complex thickness measurements after internal limiting membrane peeling in eyes with idiopathic epiretinal membrane. Invest. Ophthalmol. Vis. Sci. 2020;61(7):4240.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The purpose of this study was to verify the correlation between the microperimetry retinal sensitivity (MPRS) and the full-thickness and the ganglion cell complex (GCC) macular thickness measurements by swept-source optical coherence tomography (OCT) in eyes submitted to posterior vitrectomy with internal limiting membrane (ILM) peeling for epiretinal membrane (ERM) treatment.

Methods : In this cross-sectional, observational clinical study, fifteen-eyes of 15 patients were included. The control group included 10 contralateral eyes with no signs of ERM. The best-corrected visual acuity (BCVA), full-thickness and GCC measurements, divided in 9 sectors, were assessed. MPRS of corresponding 9 sectors macular area were assessed at least 6 months after the posterior vitrectomy with ERM and ILM peeling surgery. Inter-ocular comparisons were performed using paired T-test. Correlations between BCVA, MPRS and OCT parameters were analyzed using Spearman rank correlation (P<0.05).

Results : Patients mean age was 72.07 years (range 56-84). The mean time after surgery was 11.87 months (range 6-30). All OCT parameters were significantly reduced after surgery (P<0.01). Comparing to control eyes, OCT full-macular thickness after surgery were significantly higher in the fovea and in the 4 inner sectors for full-macular thickness. MPRS values were significantly lower in affected eyes 6 months after surgery in 5 out of 9 sectors, as well as for the mean sensitivity. Postoperative BCVA did not correlate with any OCT thickness parameter before and after surgery. MPRS correlated negatively with OCT thickness before the surgery and positively after. Average GCC thickness showed higher correlations with the MPRS parameters, both before and after surgery.

Conclusions : All OCT macular thickness were reduced after surgery. The full-macular thickness remains thicker after surgery without BCVA correlation. MPRS correlates better with OCT when compared to the BCVA, specially for the GCC layer thickness. Our results demonstrated that the inner retinal integrity plays an important role to the visual function after ERM surgery.

This is a 2020 ARVO Annual Meeting abstract.

 

A:OCT Macular thickness ETDRS map.B:Schematic representation of 44 microperimetry tested points.

A:OCT Macular thickness ETDRS map.B:Schematic representation of 44 microperimetry tested points.

 

A:Microperimetry report of a normal eye.B:eye submitted to posterior vitrectomy.

A:Microperimetry report of a normal eye.B:eye submitted to posterior vitrectomy.

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