June 2020
Volume 61, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2020
Choroiodal Neovascularization detected with OCT-Angiography in patients with CSC; Pachychoroid Neovasculopathy
Author Affiliations & Notes
  • Young-Joon Jo
    Chungnam National University, Daejeon, Korea (the Republic of)
  • Footnotes
    Commercial Relationships   Young-Joon Jo, None
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    Support  none
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 4812. doi:
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    • Get Citation

      Young-Joon Jo; Choroiodal Neovascularization detected with OCT-Angiography in patients with CSC; Pachychoroid Neovasculopathy. Invest. Ophthalmol. Vis. Sci. 2020;61(7):4812.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To report cases of CNV detected with OCT-A in patients diagnosed with CSC and to analyze the response of anti-VEGF injections

Methods : We retrospectively evaluated the fundus, FA, ICGA, OCT and OCT-A(Zeiss Elite, SS-OCTA) of consecutive 65 chronic CSC patients. Outer retina choriocapillaris(ORCC) slab and choriocapillaris(CC) slab was used to detect CNV. Anti-VEGFs were injected in cases of CNV detected with OCT-A. The response of anti-VEGF was evaluated with B-scan OCT and OCT-A.

Results : 30 of 65 consecutive chronic CSC patients had irregular PEDs detected with B-scan OCT. 8 of 30 irregular PEDs had CNV detected with OCT-A and these CNVs had not been diagnosed with FA, ICGA and B-scan OCT. There were no polyps in ICGA, So these cases must be pachychoroid Neovasculopathy(PNV). 7 of 8 had relatively thick choroid and 1 had thin choroid with pachyvessel (case 5). Anti-VEGF injections successfully reduced subretinal fluid in all cases, but 6 of 8 patients required repeated anti-VEGF injections and PDT was done in 1 recurrent case. The size and shape of CNV was not much changed with anti-VEGF injections, but in 1 PDT case, the size of CNV was decreased. In 2 patients, small subretinal hemorrhage developed after focal laser treatment. Focal laser might rupture Bruch membrane to induce new CNV or to activate the preexisting small CNV.

Conclusions : OCT-A was the only imaging modality to detect PNV and these lesions were well responded with repeated anti-VEGF injections with B-scan OCT monitoring. Focal laser should be performed with caution, especially in juxtafoveal lesion. In recurrent cases, PDT might be considered.

This is a 2020 ARVO Annual Meeting abstract.

 

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