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Rongrong Le, Yanqian Xie, huanhuan cheng, shaodan zhang, Yuxuan Deng, Yuanbo Liang; Modified canaloplasty in the Treatment of Pediatric Glaucoma: a preliminary report. Invest. Ophthalmol. Vis. Sci. 2020;61(7):952.
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We invent a new surgical procedure, penetrating canaloplasty，in which we made an opening into anterior chamber at the anterior bed of deep sclerectomy and do an iridectomy at corresponding site after routine ab external canaloplasty. Through the opening of trabecular meshwork, the aqueous humor can directly flow into Schlemm's canal and the internal filtering is achieved. This study is to evaluate the safety and efficacy of this surgery in the treatment of pediatric glaucoma.
21 eyes of 14 pediatric glaucoma patients diagnosed as pediatric glaucoma were included. 19 eyes of 12 subjects were successfully completed penetrating canaloplasty. The postoperative intraocular pressure(IOP) and complications during the first year after surgery were observed.
The IOP decreased from 30.1 ± 7.5 mmHg at baseline, to 14.4± 4.8 mmHg, 14.3 ± 4.2 mmHg, 14.2 ± 4.3 mmHg, 14.5 ± 3.9 mmHg and 15.4 ± 4.6 mmHg at 1week and 1, 3, 6,12 months respectively after surgery. Mean medication was 2.58 ± 1.2 before surgery, and it decreased to 0, 0, 0.05 ± 0.22 and 0.2 ± 0.6 at 1week and 1, 3, 6, 12 months post-surgery respectively. The unqualified success rate of the subjects was 89.5 %, 94.7 %, 94.7 %, 89.5%, 95% at 1week and 1, 3, 6, 12 months post-surgery respectively. No bleb and no severe complications occurred after surgery.
Penetrating canaloplasty, as a new internal filtering surgical procedure, was a safe and effective way to reduce IOP in children with pediatric glaucoma.
This is a 2020 ARVO Annual Meeting abstract.
Fig 1 A-Intraoperative photograph. B-Schematic diagram of surgery. After the suture was placed, the deep trabecular tissue between Schlemm’s canal and the cornea, as well as the iris root was cut (arrow).
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