June 2020
Volume 61, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2020
Comparison of 24-2C SITA Standard test times to legacy SITA tests
Author Affiliations & Notes
  • Gary C Lee
    Carl Zeiss Meditec, Inc, Dublin, California, United States
  • Thomas Callan
    Carl Zeiss Meditec, Inc, Dublin, California, United States
  • Sophia Yu
    Carl Zeiss Meditec, Inc, Dublin, California, United States
  • Mary K Durbin
    Carl Zeiss Meditec, Inc, Dublin, California, United States
  • Nolleisha Graves
    Carl Zeiss Meditec, Inc, Dublin, California, United States
  • Charles Wu
    Carl Zeiss Meditec, Inc, Dublin, California, United States
  • Iryna Falkenstein
    Glaucoma Specialists of San Francisco, Oakland, California, United States
  • Todd Severin
    East Bay Eye Center, San Ramon, California, United States
  • Footnotes
    Commercial Relationships   Gary Lee, Carl Zeiss Meditec, Inc. (E); Thomas Callan, Carl Zeiss Meditec, Inc. (E); Sophia Yu, Carl Zeiss Meditec, Inc. (E); Mary Durbin, Carl Zeiss Meditec, Inc. (E); Nolleisha Graves, Carl Zeiss Meditec, Inc. (C); Charles Wu, Carl Zeiss Meditec, Inc. (C); Iryna Falkenstein, Carl Zeiss Meditec, Inc. (C); Todd Severin, Carl Zeiss Meditec, Inc. (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2020, Vol.61, 3879. doi:
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      Gary C Lee, Thomas Callan, Sophia Yu, Mary K Durbin, Nolleisha Graves, Charles Wu, Iryna Falkenstein, Todd Severin; Comparison of 24-2C SITA Standard test times to legacy SITA tests. Invest. Ophthalmol. Vis. Sci. 2020;61(7):3879.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The 24-2C test pattern includes 10 test locations from the 10-2 pattern, selected to increase sensitivity to central field defects, that are tested at the end of a 24-2 threshold test. The purpose of this ongoing, preliminary clinical study was to compare the durations of a prototype 24-2C SITA Standard test to legacy SITA tests in normal and glaucomatous eyes.

Methods : Experimental 24-2C SITA Standard (SS-C), as well as 24-2C SITA Faster (SFR-C), 10-2 SITA Standard (SS-10), and 10-2 SITA Fast (SF-10) visual fields (VFs) were acquired on an HFA3 Model 860 perimeter (ZEISS, Dublin, CA) at each of two visits on one eye each for normal and glaucomatous subjects. 24-2 SITA Faster (SFR) and 24-2 SITA Standard (SS) VFs were extracted from SS-C and SFR-C, respectively. Second visit data were used for analyses. Summary statistics and significance testing (α = 0.05) were used to compare the durations of SS-C to the other tests, including combinations of SS+SS-10 and SFR+SF-10 representing the additional time for a second VF.

Results : Mean age was 55.3 (standard deviation, SD: 7.7; range: 44.3 to 69.9) years for 13 normal eyes and 70.5 (SD: 6.0; range 60.9 to 81.0) years for 13 glaucomatous eyes (P<0.001). Mean MDSS was 0.52 (SD: 0.69; range: -0.62 to 1.79) dB and -6.21 (SD: 7.55; range: -23.16 to 1.63) dB in normal and glaucomatous eyes (P=0.008), respectively. SS-Cadded 31 to 46 seconds (~10%) to SS test durations (P<0.001) in both cohorts (See Table 1). SS-C was comparable in test time to both SS-10 and SFR+SF-10 (P>0.05), with mean differences within ±4%, and was nearly twice as fast as SS+SS-10 (See Fig 1). SS-C was also slower than SFR, SFR-C, and SF-10 on average (P<0.001).

Conclusions : The findings in this preliminary cohort suggest 24-2C SITA Standard test times are comparable to legacy 10-2 and 24-2 SITA Standard tests taken individually, with a small increase in test time for the 10 additional central test locations. Based on test times, in cases where users would like to perform additional testing in the central VF to detect field loss, such as presence of parafoveal lesions on OCT, 24-2C SITA Standard may provide a clinical alternative to acquiring an additional 10-2 VF along with 24-2 SITA Standard. This option may also be a suitable alternative if switching to faster SITA tests (e.g. 24-2 SITA Faster plus 10-2 SITA Fast) is not preferred.

This is a 2020 ARVO Annual Meeting abstract.

 

Table 1. Summary of durations

Table 1. Summary of durations

 

Figure 1. Mean ± standard errors of durations

Figure 1. Mean ± standard errors of durations

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