Abstract
Purpose :
Xephilio OCT-S1 (Canon) can capture up to a 23×20 mm wide-field OCTA image with a single photograph and is also able to capture high resolution images using artificial intelligence.
We aimed to evaluate the ability of wide-field OCTA using Xephilio OCT-S1 to detect retinal neovascularization (NV) in eyes with proliferative diabetic retinopathy (PDR).
Methods :
This retrospective study included 38 eyes of 21 patients (age, 54±10 years old; 8 females, 13 males) with PDR. All patients underwent a comprehensive ophthalmological examination, including fluorescein angiography (FA) as well as both fovea centered (Fig. 1) and disc centered (Fig. 2) 23×20 mm OCTA imaging (A-scan/B-scan, 928/807). The number of neovascularization sites identified with FA and the number identified with OCT B-scan, a vitreous retinal interface slab and a superficial retinal slab of the wide-field OCTA images, including the position of the neovascularization (nasal upper, nasal lower, temporal upper, temporal lower or disc), were compared and examined.
Results :
A total of 102 NV (18/26/29/21/8) were identified with FA. Fovea centered 23×20 mm OCTA images were able to visualize 97 (95%) of the NV (14/25/2/21/8). This method tended to miss nasal neovascularization. In contrast, disc centered 23×20 mm OCTA images were able to visualize almost all of the NVs, detecting 101 (99%) of the NV (18/26/28/21/8). It was possible to visualize all the NV using two wide-field OCTA images, fovea and disc centered.
Conclusions :
The wide-field (23×20 mm) OCTA using Xephilio OCT-S1 can identify almost all PDR NV with a single photograph, in particular disc centered. Therefore, it appears to be clinically useful.
This is a 2020 ARVO Annual Meeting abstract.