Abstract
Purpose :
To evaluate the association between intake of dietary nutrition and open angle glaucoma (OAG) stratified by obesity in Korean.
Methods :
A population-based, cross-sectional survey was performed from the Korean National Health and Nutrition Examination Survey between 2010-2011 and subjects who answered nutritional survey and underwent ophthalmic evaluation(n=6,742) enrolled. All subjects were stratified according to gender and obesity based on body mass index (BMI). Dietary intake was determined using the 24 hour recall method. Multivariate regression analysis was used to assess the correlation between intake of dietary nutrition and the prevalence of OAG.
Results :
The prevalence of OAG among study participants was 4.79%. In multiple linear regression models with stratified by gender and BMI, in low BMI group (BMI<18.5), females with OAG showed significant association with lower intake of energy, protein, fat, carbohydrate, ash, calcium, phosphorus, sodium, potassium, vitamin A, B-carotene, thiamin, riboflavin and vitamin C than non-glaucoma group by multivariate logistic regression analysis (all p < 0.05). The medium BMI group (18.5≤BMI<23) showed significant lower intake of food, energy, protein, calcium, phosphorus, potassium, thiamin and niacin by multivariate logistic regression analysis. (all p < 0.05). In high BMI group (25＞BMI ≥23), only intake of vitamin C showed significant difference. In male, lower intake of protein and thiamine was only significantly related factor with OAG of medium BMI males. Obese group (BMI ≥ 25) didn’t show significant finding.
Conclusions :
Intake of dietary nutrition was associated with the development of glaucoma in female subjects with low BMI. Insufficient intake of certain nutrients may be associated with an increased risk of glaucoma in female. Further large scale cohort studies are needed to determine whether the specific nutrients have an effect on the risk of glaucoma.
This is a 2020 ARVO Annual Meeting abstract.