July 2020
Volume 61, Issue 9
Free
ARVO Imaging in the Eye Conference Abstract  |   July 2020
Enducope-integrated common-path interferometer for Schlemm’s canal imaging and targeting.
Author Affiliations & Notes
  • Haroun Al-Mohamedi
    University-Eye-Hospital Tuebingen, Tuebingen, Germany
    Foundation for Research in Ophthalmology, Tübingen, Germany
  • Andreas Prinz
    University-Eye-Hospital Tuebingen, Tuebingen, Germany
    Foundation for Research in Ophthalmology, Tübingen, Germany
  • Thomas Bende
    University-Eye-Hospital Tuebingen, Tuebingen, Germany
    Foundation for Research in Ophthalmology, Tübingen, Germany
  • Michael S. Berlin
    Stein Eye Institute, University of California, California, United States
  • Footnotes
    Commercial Relationships   Haroun Al-Mohamedi, None; Andreas Prinz, None; Thomas Bende, None; Michael S. Berlin, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2020, Vol.61, PB00129. doi:
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    • Get Citation

      Haroun Al-Mohamedi, Andreas Prinz, Thomas Bende, Michael S. Berlin; Enducope-integrated common-path interferometer for Schlemm’s canal imaging and targeting.. Invest. Ophthalmol. Vis. Sci. 2020;61(9):PB00129.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Feasibility study for targeting Schlemm’s canal (SC) and overlying trabecular meshwork from across the anterior chamber without a goniolens or contrast agent by using a Enducope-integrated common-path interferometer to enable goniolens free Excimer Laser Trabeculotomy (ELT) Micro-invasive glaucoma surgery (MIGS).

Methods : A common-path interferometer tissue recognition and distance sensor is integrated into the ELT- Handpiece. A drilled quartz rods ( 1mm diameter) imager designed specifically for the purpose of sensing and imaging Schlemm’s canal, ab-interno is used in a model system to determine whether this imager is able to generate guidance information useful to enable goniolens-free ELT surgery.

Results : The 1300 nm interferometer wavelength enables adequate signal to noise data to be clinically useful for sensing and imaging Schlemm’s canal in this in vitro model. The SNR was 68 dB, the measuring depth averaged 10mm and the resolution was <= 8 µm.

Conclusions : This integrated technology and technique enables the identification and localization of Schlemm’s canal distal to the trabecular meshwork by means of a non contact intraocular fiberoptic probe without direct goniolens visualization.

This is a 2020 Imaging in the Eye Conference abstract.

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