The authors thank Duco Hamasaki (Bascom Palmer Eye Institute) for the discussions and editing the final version of the manuscript, as well as Yukihide Momozawa and the members of the Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences.
Supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (grant 19K09928 to SU) and Takayanagi Retina Research Award (to SU).
Disclosure: Y. Koyanagi, None; S. Ueno, Novartis Pharma K.K. (F), Tomey Corporation (F), Nidek Company (F), Canon Life Care Solutions (F), HOYA Company (F); Y. Ito, Alcon Japan (F), Bayer Health Care (F), Canon Life Care Solutions (F), Carl Zeiss Meditec (F), Kowa Pharmaceutical (F), Novartis Pharma K.K. (F), Pfizer Japan (F), Santen Pharmaceutical (F); T. Kominami, None; S. Komori, None; M. Akiyama, Nidek Company (F); Y. Murakami, None; Y. Ikeda, Nidek Company (F), HOYA Corporation (F, C), Otsuka Pharmaceutical (F), Santen Pharmaceutical (F), Novartis Pharma K.K. (F), Senju Pharmaceutical (F), Kowa Pharmaceutical (F), Bayer Health Care (F); K.-H. Sonoda, None; H. Terasaki, Nidek Company (F), Rohto Pharmaceutical (F), Otsuka Pharmaceutical (F), Pfizer Japan (F), Santen Pharmaceutical (F), Alcon Japan (F), Novartis Pharma K.K. (F), Carl Zeiss Meditec (F, C), Senju Pharmaceutical (F), Kowa Pharmaceutical (F), Bayer Health Care (F, C), Wakamoto (F), HOYA Corporation (F), Astellas Pharma (F), Ono Pharmaceutical (C), Sanwa Kagaku Kenkyusho (F), Aichi Ophthalmologists Association (F), Nitten Pharmaceutical (F), Takeda Pharmaceutical Company (F), Chiba Ophthalmologist Association (F), Japan Medical Association (F), Fukushima Ophthalmologist Association (F)