Patients diagnosed with glaucoma who had developed any episode of PPRS in the follow-up period were included, and the entire medical records were used for the analysis.
The exclusion criteria were (1) conditions that could produce retinal edema, including optic disc coloboma, congenital optic pit maculopathy, or severe epiretinal membrane; (2) poor-quality optical coherence tomography (OCT) scans; and (3) fewer than three visits with sets of glaucoma examinations, comprising the simultaneous VF test, color and red-free photographs, and OCT.
Measurements of visual acuity and refraction; Goldmann applanation tonometry for intraocular pressure (IOP); slit-lamp biomicroscopy with gonioscopy; dilated stereoscopic examination of the ONH; color, red-free, and infrared fundus photography; Humphrey Swedish interactive threshold algorithm VF tests using the central 30-2 Humphrey field analyzer (HFA model 640 or model 740; Humphrey Instruments Inc., San Leandro, CA, USA); and spectral-domain OCT with Cirrus HD-OCT (Carl Zeiss Meditec, Inc., Dublin, CA, USA) were performed annually. At least one enhanced-depth imaging examination of ONH with the Spectralis OCT (Heidelberg Engineering GmBH, Dossenheim, Germany) was performed for all patients. Patients were routinely followed up with glaucoma examinations every six to 12 months, and additional visits and examinations with shorter intervals of three to six months were planned according to their condition, such as suspicious glaucoma progression, which requires additional tests for confirmation, recent rapid progression, or an increasing IOP trend.