June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Corneal Crosslinking Intracorneal Stress Measured by a Novel and Easily Implemented Differential Tonometry Method
Author Affiliations & Notes
  • Sean Joseph McCafferty
    Ophthalmology, Banner University Medical Center Tuscon, Tucson, Arizona, United States
  • Mingwu Wang
    Ophthalmology, Banner University Medical Center South, Tucson, Arizona, United States
  • Footnotes
    Commercial Relationships   Sean McCafferty, Intuor Technologies (I), Reichert (C); Mingwu Wang, None
  • Footnotes
    Support  NEI R43 EY026821-01
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 767. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Sean Joseph McCafferty, Mingwu Wang; Corneal Crosslinking Intracorneal Stress Measured by a Novel and Easily Implemented Differential Tonometry Method. Invest. Ophthalmol. Vis. Sci. 2021;62(8):767.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Evaluate corneal changes following corneal crosslinking (CXL) by paired differential tonometry intraocular pressure (IOP) measurements with a Goldmann tonometer (GAT) prism and corneal compensating, correcting applanation tonometry surface (CATS) prism.

Methods : Design: Prospective, controlled, open-label reference device comparison
Methods: IOP was measured on 23 unique eyes undergoing CXL for keratoconus with a GAT using a standard flat GAT prism and a curved corneal error correcting CATS prism before treatment and at 2 weeks, 2 months and 6 months after treatment. Concurrent measurements of central corneal thickness (CCT) and corneal hysteresis (CH) were completed.

Results : Randomized paired IOP measurements with standard GAT and corneal correcting CATS prisms indicated a significant sustained relative increase in the differential IOP between the two prisms after CXL (p=0.005,0.015,0.001). CH initially decreased at two weeks post-CXL then returned to sustained pre-op levels (p=0.033,0.20,0.20). CCT progressively decreased following CXL (p=0.005).

Conclusions : Differential tonometry between standard GAT and corneal biomechanical compensating CATS prisms demonstrates a simple and sensitive method for measurement of changes in corneal rigidity and corneal stress redistribution. Results suggest that CXL likely re-establishes a more “normal” biomechanical behavior to the keratoconic cornea.

This is a 2021 ARVO Annual Meeting abstract.

 

Corneal Cross-linking likely re-establishes a more “normal” biomechanical behavior to the keratoconic cornea.

Corneal Cross-linking likely re-establishes a more “normal” biomechanical behavior to the keratoconic cornea.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×