Purchase this article with an account.
Michael Doyle, Gary C Lee, Sophia Yu, Mary K Durbin, Noelleisha Graves, Charles Wu, Todd Severin, Iryna Falkenstein, Thomas Callan; Comparison of 24-2C SITA Standard intervisit repeatability to legacy SITA tests. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3362.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
The 24-2C test pattern increases sensitivity to central field defects by adding 10 test locations from the 10-2 pattern that are tested at the end of a 24-2 threshold test1. The purpose of this ongoing, preliminary clinical study was to compare the repeatability of the 10 added test locations in a prototype 24-2C SITA Standard test to legacy SITA tests in normal and glaucomatous eyes.
Experimental 24-2C SITA Standard (SS-C), as well as 24-2C SITA Faster (SFR-C), 10-2 SITA Standard (SS-10), and 10-2 SITA Fast (SF-10) visual fields (VFs) were acquired on an HFA3 Model 860 perimeter (ZEISS, Dublin, CA) at each of two visits on one eye each for healthy and glaucomatous subjects. 24-2 SITA Standard VFs were extracted from SS-C as a reference for disease severity.Repeatability was calculated by computing the test-retest standard deviation (TRT-SD) using both visit data for mean deviation (MD) and pattern standard deviation (PSD), as well as individual threshold values at the 10 added test locations.
Mean age was 55.8 (standard deviation, SD: 6.4; range: 44.3 to 69.9) years for 17 healthy eyes and 73.6 (SD: 9.2; range 60.9 to 97.9) years for 16 glaucomatous eyes (p<0.001). Mean 24-2 SITA Standard MD was 0.63 (SD: 1.15; range: -1.14 to 3.04) dB and -6.81 (SD: 6.86; range: -22.61 to 1.85) dB in healthy and glaucomatous eyes (p<0.001), respectively.TRT-SDs for MD were 0.61, 1.29, 0.52, and 0.49 dB for tests SS-C, SFR-C, SS-10, and SF-10, respectively.TRT-SDs for the 10 added locations were 1.57, 2.28, 1.85, 2.21 dB for tests SS-C, SFR-C, SS-10, and SF-10, respectively (see Table 1). Overall, the repeatability for SS-C MD and thresholds were comparable to their counterparts.
The findings in this preliminary cohort suggest the repeatability of the additional test locations added to 24-2C SITA Standard test is comparable to the repeatability of the same locations in the 24-2C SITA Faster and the 10-2 SITA tests. As a result, a 24-2C SITA Standard test may maintain comparable ability to detect progressive changes in the ten new test locations in the central visual field as compared to the current SITA tests.References Callan et al. IOVS 2020; 61(7): Abstract 3876
This is a 2021 ARVO Annual Meeting abstract.
Table 1. TRT-SD and 95% confidence interval for thresholds in the 10 new test locations
This PDF is available to Subscribers Only