Effect of Myopia Control Spectacle Lenses with Aspherical Lenslets on Choroidal Thickness in Myopic Children: 1-Year Results

Abstract

Purpose : Choroidal thinning is usually associated with myopia progressing. This study aimed to assess changes in choroidal thickness (ChT) in Chinese children wearing two new types of myopia control spectacle lenses with concentric rings of contiguous aspherical lenslets over a period of one year.

Methods : Within arandomized, controlled, double-masked clinical trial,160 children (age 8 to 13 years, myopia between -0.75 D and -4.75 D) wore either spectacles lenses with highly aspherical lenslets (HAL), slightly aspherical lenslets (SAL) or single-vision lenses (SVL). We acquired ChT form central 6 mm radial OCT scans (Topcon Triton) at the baseline, 6 months, and 12 months. The changes from the baseline were compared between groups at foveal locations according to the Early Treatment Diabetic Retinopathy Study (ETDRS) areas.

Results : After one year, the ChT decreased at all regions in the SVL group by up to -10.29 ± 20.11 µm in the central fovea. This trend was significantly less pronounced in all regions in the SAL group (p < 0.05) that showed a maximal thinning of -2.94 ± 21.78 µm also in the central fovea. Most remarkably, the HAL group exhibited an increase in choroidal thickness in all regions by up to 18.24 ± 18.22 µm in the superior regions and this effect was significantly different from both SVL and SAL (p < 0.05).

Conclusions : We observed the expected choroidal thinning associated with myopia progression in the SVL group. Wearing SAL lenses reduced this effect and wearing HAL lenses reversed this effect. These results are in agreement with the superior myopia control effect of the HAL lenses.

This is a 2021 ARVO Annual Meeting abstract.