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Matthew D Karl, William R Bloom, Matthew P. Ohr; Assessing Outcomes in Pars Plana Vitrectomy for Epiretinal Membrane using Indocyanine Green versus Brilliant Blue. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3661.
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© ARVO (1962-2015); The Authors (2016-present)
The objective of this single institution retrospective chart review study is to assess visual outcomes in patients who underwent pars plana vitrectomy with membrane peel for epiretinal membrane using indocyanine green (ICG) versus brilliant blue (BB) dye.
A retrospective chart review was performed for patients who underwent pars plana vitrectomy for epiretinal membrane between April 1, 2012 and April 1, 2020. Data collected included de-identified demographics, visual acuity (VA), and optical coherence tomography (OCT) central macular thickness (CMT) through post operative month (POM) three.
60 eyes of 60 patients were included. 23 eyes received intraoperative BB, 37 received intraoperative ICG. There was no significant difference in baseline VA or CMT. No significant difference in VA or CMT was found in patients receiving intraoperative ICG versus BB during pars plana vitrectomy for epiretinal membrane from baseline to POM three (VA: -0.15 ± .25 with ICG and -0.16 ± .23 with BB, p = 0.90; -78.8 ± 87.4 with ICG and -98.7 ± 78.4 with BB, p = 0.36). Patients receiving ICG had a greater improvement in VA from baseline to POM one than patients receiving BB (-0.17 ± 0.24 with ICG and -0.03 ± 0.26 with BB, p = 0.04), however that difference did not persist through the end of the follow up period. Results are summarized in Table 1.
No significant difference was found between VA or CMT in patients receiving intraoperative ICG versus BB, suggesting both of these vital dyes are safe to use during pars plana vitrectomy for epiretinal membrane removal. This study may be limited by sample size and short follow up.
This is a 2021 ARVO Annual Meeting abstract.
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