June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Retinal damage extends beyond the retinal detachment
Author Affiliations & Notes
  • Heijan Ng
    Rotterdams Oogheelkundig Instituut, Rotterdam, Zuid Holland, Netherlands
  • Koenraad Arndt Vermeer
    Rotterdams Oogheelkundig Instituut, Rotterdam, Zuid Holland, Netherlands
  • Ellen La Heij
    Oogziekenhuis Rotterdam, Rotterdam, South Holland, Netherlands
  • Caroline Kuip
    Rotterdams Oogheelkundig Instituut, Rotterdam, Zuid Holland, Netherlands
  • jan van meurs
    Oogziekenhuis Rotterdam, Rotterdam, South Holland, Netherlands
    Erasmus MC, Rotterdam, Zuid-Holland, Netherlands
  • Footnotes
    Commercial Relationships   Heijan Ng, None; Koenraad Vermeer, None; Ellen La Heij, None; Caroline Kuip, None; jan van meurs, None
  • Footnotes
    Support  Stichting voor Ooglijders (Rotterdam, the Netherlands) and Stichting Wetenschappelijk Onderzoek Oogziekenhuis (Rotterdam, the Netherlands)
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 3659. doi:
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    • Get Citation

      Heijan Ng, Koenraad Arndt Vermeer, Ellen La Heij, Caroline Kuip, jan van meurs; Retinal damage extends beyond the retinal detachment. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3659.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Despite anatomically successful surgery for fovea-on rhegmatogenous retinal detachment (RD), unexplainable loss of vision is regularly observed in these patients. We hypothesize that the retinal function loss induced by the RD extends beyond the detached area, towards the fovea. Thus, the aim of this study is to investigate the retinal sensitivity loss in relation to the distance to the RD border in patients with fovea-on rhegmatogenous RD.

Methods : We prospectively evaluated 15 patients with fovea-on RD and healthy fellow eye. Preoperatively, OCT-scans of the RD border were obtained (Spectralis-OCT2, Heidelberg Engineering). The RD border was located on the B-scans and highlighted on the SLO-image.
Microperimetry (MAIA, Centervue) was performed using a custom grid of 52 points covering the RD border and the retina on both sides. The macular area was investigated using the standard foveal centered grid of 37 points covering a circular area of 10° in diameter (Figure 1). At 6 weeks postoperatively, microperimetry was performed in the fellow eye, covering the same areas as in the study eye.
Microperimetry data was overlaid on the SLO-image and the RD border was indicated; for each sensitivity measurement, the shortest distance to the RD border was calculated. Loss of retinal sensitivity was calculated as the difference in sensitivity between the study and the control eye at each corresponding location (study-control). The relation between retinal sensitivity loss and the distance to the RD border was assessed using a locally weighted scatterplot smoothing (LOWESS) curve.

Results : Retinal sensitivity loss was 22 dB at 3° inside the RD and decreased approximately linearly to 4 dB at 2° outside the RD. The loss further decreased outside the RD until it reached a plateau of 2 dB at 6° (Figure 2).

Conclusions : Retinal sensitivity loss extends beyond the RD border towards the fovea. These results may explain the loss of vision in patients in whom the fovea has not been detached.

This is a 2021 ARVO Annual Meeting abstract.

 

Figure 1:Preoperative microperimetry examination of an eye with fovea-on retinal detachment. The red line represents the retinal detachment border as determined from OCT scans.

Figure 1:Preoperative microperimetry examination of an eye with fovea-on retinal detachment. The red line represents the retinal detachment border as determined from OCT scans.

 

Figure 2:Preoperative retinal sensitivity loss in relation to the distance to the retinal detachment border in patients with fovea-on retinal detachment (n=15). The red line is the locally weighted scatterplot smoothing curve. The light red area around the curve represents the 95% confidence interval.

Figure 2:Preoperative retinal sensitivity loss in relation to the distance to the retinal detachment border in patients with fovea-on retinal detachment (n=15). The red line is the locally weighted scatterplot smoothing curve. The light red area around the curve represents the 95% confidence interval.

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