June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Slit-scanning ophthalmoscopy to measure ultra-widefield peripheral refraction along nasal/temporal and superior/inferior meridians
Author Affiliations & Notes
  • Katharina G. Foote
    Carl Zeiss Meditec Inc, Dublin, California, United States
  • Conor Leahy
    Carl Zeiss Meditec Inc, Dublin, California, United States
  • Matt Everett
    Carl Zeiss Meditec Inc, Dublin, California, United States
  • Jochen Straub
    Carl Zeiss Meditec Inc, Dublin, California, United States
  • Footnotes
    Commercial Relationships   Katharina Foote, Carl Zeiss Meditec, Inc. (E); Conor Leahy, Carl Zeiss Meditec, Inc. (E); Matt Everett, Carl Zeiss Meditec, Inc. (E); Jochen Straub, Carl Zeiss Meditec, Inc. (E)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 2877. doi:
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      Katharina G. Foote, Conor Leahy, Matt Everett, Jochen Straub; Slit-scanning ophthalmoscopy to measure ultra-widefield peripheral refraction along nasal/temporal and superior/inferior meridians. Invest. Ophthalmol. Vis. Sci. 2021;62(8):2877.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Autorefractors typically measure over a limited range of visual field angles. Retinal imaging, particularly ultra-widefield (UWF) imaging, has demonstrated utility in visualizing the periphery. UWF slit-scanning ophthalmoscopes can measure peripheral refraction over a wider field of view (FOV) and are faster and easier to use than open-field autorefractors. A prospective study was performed to examine UWF imaging feasibility to extend peripheral refraction measurement range to a full 130°.

Methods : A modified widefield slit-scanning ophthalmoscope (CLARUS™ 500, ZEISS, Dublin, CA) with prototype software was used to test 5 subjects with spherical equivalent refractions ranging from -12.25D to 0.00D. In order to capture overlapping 90° fields, images were acquired with the internal fixation at central position, and then with ±20° offsets along each meridian. The vertical component of refraction over the full FOV was determined from the slit-scan data. Fundus features were used to co-register and merge the fields, resulting in a 130° peripheral refraction map.

Results : An extended view of UWF peripheral refraction was obtained for emmetropic and myopic subjects. In Fig 1, a sample UWF absolute peripheral refraction map is shown. In Fig 2, relative peripheral refraction along the full nasal/temporal and superior/inferior meridians is displayed. These measures were computed from an average of 1° strip for each subject. Most myopic subjects show characteristic relative peripheral hyperopia along the nasal/temporal meridian and relative myopia along the superior/inferior meridian. Lid/lash artifacts prevented a full range of measurements in superior/inferior regions.

Conclusions : This study demonstrated a capability of providing data on an unprecedented FOV. Peripheral refraction measurements acquired on myopic eyes followed established trends. Consistent with literature, this study showed hyperopia increases more in the nasal/temporal field than in the superior/inferior field. This measurement technique could be useful for enhancing research in the field of myopia.

This is a 2021 ARVO Annual Meeting abstract.

 

Figure 1. Example UWF fundus map of peripheral refraction for myopic eye (SID 243). Lid/lash artifacts appear in gray.

Figure 1. Example UWF fundus map of peripheral refraction for myopic eye (SID 243). Lid/lash artifacts appear in gray.

 

Figure 2. Plots of relative peripheral refractive error for each subject. The range of accurate measurement along the superior/inferior meridian was generally limited by lid/lash artifacts.

Figure 2. Plots of relative peripheral refractive error for each subject. The range of accurate measurement along the superior/inferior meridian was generally limited by lid/lash artifacts.

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