June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Purposeful Pneumatic Induced Resorption of Submacular Fluid in Macula-off Retinal Detachments
Author Affiliations & Notes
  • Siyang Chaili
    Vanderbilt Eye Institute, Nashville, Tennessee, United States
  • John Fitzpatrick
    Vanderbilt Eye Institute, Nashville, Tennessee, United States
  • Ash Pirouz
    Retina Consultants of Orange County, Fullerton, California, United States
  • Scott Grant
    Retina Consultants of Orange County, Fullerton, California, United States
  • Sean Adrean
    Retina Consultants of Orange County, Fullerton, California, United States
  • Footnotes
    Commercial Relationships   Siyang Chaili, None; John Fitzpatrick, None; Ash Pirouz, None; Scott Grant, None; Sean Adrean, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 3677. doi:
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    • Get Citation

      Siyang Chaili, John Fitzpatrick, Ash Pirouz, Scott Grant, Sean Adrean; Purposeful Pneumatic Induced Resorption of Submacular Fluid in Macula-off Retinal Detachments. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3677.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate visual outcomes in eyes with macula-off retinal detachments (RD) with purposeful submacular fluid retention after vitrectomy to allow for slow pneumatic macular flattening.

Methods : Retrospective study of 139 patients with macula-off RD. Patients were included if repaired with primary vitrectomy (VIT) or VIT with scleral buckle (SB). Patients were excluded if they had >6 wks to surgery, prior vitreous surgery, SB alone, drainage retinotomy or perfluorocarbon, development of proliferative vitreoretinopathy (PVR), <6 mon follow up, or other macular pathology. Patients underwent 3-port pars plana VIT with SB. Subretinal fluid was aspirated from pre-existing retinal breaks during air-fluid exchange (AFX). At the end of surgery fluid remained in the posterior pole and SF6 or C3F8 gas was then introduced with proper head positionoing.

Results : Subretinal fluid was reabsorbed and gas fill was observed at post-op day 1. Mean baseline vision was 20.0±24.4 ETDRS letters (20/400) for 127/198 included patients. Of 71 excluded patients, 12 developed PVR. Primary repair success rate was 91.4% (127/139). Mean time to surgery was 8.6±7.9 days. At 6 months post-op, mean vision improved to 62.9±17.9 letters (20/60), an increase of 43.1±28.0 letters (8.6 lines) which was better than baseline (p<0.001). Best achieved vision averaged 72.6±13.2 letters (20/30-2), an increase of 52.8±25.1 letters (9.5 lines), at an average of 14.1±11.0 months later (p<0.001 vs baseline & 6 months post-op). Mean time to final follow-up was 25.8±26.5 months. Patients with ≥20/40 vision increased from 3.1% at baseline to 44.9% at 6 months post-op to 74.8% at best achieved vision. Conversely, patients with ≤20/200 vision decreased from 78.7% at baseline to 14.2% at 6 months post-op to 4.7% at best achieved vision.

Conclusions : Good visual outcomes may be achieved and maintained even if the duration of the macular detachment is longer than several weeks. Leaving fluid in the macula at the end of the surgery may allow the RPE pump to more physiologically remove submacular fluid, and for the photoreceptor/RPE microvilli interdigitation to anneal with better retinotopic organization, promoting visual recovery.

This is a 2021 ARVO Annual Meeting abstract.

 

Figure 1: A) Vision after repair was better than at initial presentation (p<0.001); B) More patients achieved ≥20/40 vision after repair.

Figure 1: A) Vision after repair was better than at initial presentation (p<0.001); B) More patients achieved ≥20/40 vision after repair.

 

Figure 2: Time to surgery did not influence best achieved vision or final visual outcomes.

Figure 2: Time to surgery did not influence best achieved vision or final visual outcomes.

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