June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Peripheral defocus of polymethylmethacrylate spherical optic monofocal intraocular lenses
Author Affiliations & Notes
  • Ashik Mohamed
    Ophthalmic Biophysics, L V Prasad Eye Institute, Hyderabad, Telangana, India
    Brien Holden Vision Institute Limited, Sydney, New South Wales, Australia
  • Bianca Maceo Heilman
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Sushma Nandyala
    Ophthalmic Biophysics, L V Prasad Eye Institute, Hyderabad, Telangana, India
  • Ramya Natarajan
    Ophthalmic Biophysics, L V Prasad Eye Institute, Hyderabad, Telangana, India
  • Kannan Umadevi Venkataraju
    Appasamy Ocular Devices (P) Ltd, Puducherry, Puducherry, India
  • Siobhan Williams
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Marco Ruggeri
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Jean-Marie A Parel
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States
    Brien Holden Vision Institute Limited, Sydney, New South Wales, Australia
  • Arthur Ho
    Brien Holden Vision Institute Limited, Sydney, New South Wales, Australia
    School of Optometry and Vision Science, The University of New South Wales, Sydney, New South Wales, Australia
  • Fabrice Manns
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Footnotes
    Commercial Relationships   Ashik Mohamed, None; Bianca Maceo Heilman, None; Sushma Nandyala, None; Ramya Natarajan, None; Kannan Umadevi Venkataraju, Appasamy Ocular Devices (P) Ltd (E); Siobhan Williams, None; Marco Ruggeri, None; Jean-Marie Parel, None; Arthur Ho, None; Fabrice Manns, None
  • Footnotes
    Support  The study was supported in part by National Institutes of Health Grants R01EY021834, F31EY021444 (Ruth L. Kirschstein National Research Service Award Individual Pre-doctoral Fellowship [BMH]), and Center Grant P30EY14801; Australian Government Cooperative Research Centre Scheme (Vision CRC); the Florida Lions Eye Bank; Dr. Harry W. Flynn Jr.; Drs. Karl R. Olsen and Martha E. Hildebrandt; Drs. Raksha Urs and Aaron Furtado; an unrestricted grant from Research to Prevent Blindness; the Henri and Flore Lesieur Foundation (JMP); Hyderabad Eye Research Foundation.
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 2013. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Ashik Mohamed, Bianca Maceo Heilman, Sushma Nandyala, Ramya Natarajan, Kannan Umadevi Venkataraju, Siobhan Williams, Marco Ruggeri, Jean-Marie A Parel, Arthur Ho, Fabrice Manns; Peripheral defocus of polymethylmethacrylate spherical optic monofocal intraocular lenses. Invest. Ophthalmol. Vis. Sci. 2021;62(8):2013.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To evaluate the peripheral defocus of monofocal intraocular lenses (IOLs), thereby quantifying the accuracy of laser ray tracing (LRT) measurements of peripheral defocus.

Methods : Data were acquired on 14 polymethylmethacrylate spherical optic monofocal IOLs (overall length 12.5 mm, optic diameter 6.0 mm). The power (D) of the IOLs used were 17.5, 18, 18.5, 19, 19.5, 20, 20.5, 21, 22, 22.5, 23, 23.5, 24 and 24.5. IOLs were placed in a custom-built combined LRT and optical coherence tomography (OCT) system (Ruggeri et al, BOE 2018). Ray trace experiments were performed for incidence angles ranging from -30° to +30° in 5° increments using a raster scan (6 mm x 6 mm) with 0.25 mm spacing. An image sensor mounted on a positioning stage below the IOL acquired ray-intercept spots at different axial positions and a custom program calculated the ray slopes from the spot positions. At each angle, lens power was calculated by finding the axial position that minimizes the root-mean-square diameter of the spot pattern formed by the central 169 rays corresponding to the central 3 mm zone. For each IOL, the measured relative peripheral defocus (Figure 1) was compared to the value obtained using optical theory. The theoretical peripheral defocus was the position of the circle of least confusion calculated assuming that the IOL is a thin lens with the aperture stop located at the plane of the lens.

Results : The measured peripheral defocus (D) increased significantly (all p≤0.001) with increasing incidence angle (IOL power adjusted mean of +0.27, +0.78, +1.85, +3.25, +5.54 and +8.60 at ±5°, ±10°, ±15°, ±20°, ±25° and ±30° respectively). The IOL power mean difference (D) between the measured and predicted peripheral defocus (Figure 2) was +0.03, -0.21, -0.24, -0.74, -0.76 and -0.59 at ±5°, ±10°, ±15°, ±20°, ±25° and ±30° respectively.

Conclusions : The IOL power increases with increasing field angle corresponding to a shift towards myopic peripheral defocus. The LRT-OCT system accurately measures the peripheral power.

This is a 2021 ARVO Annual Meeting abstract.

 

Figure 1: Scatterplot showing the relative peripheral defocus (difference between off-axis and on-axis power) for each intraocular lens at various delivery angles.

Figure 1: Scatterplot showing the relative peripheral defocus (difference between off-axis and on-axis power) for each intraocular lens at various delivery angles.

 

Figure 2: Scatterplot showing the difference between the measured and predicted peripheral defocus for each intraocular lens at various delivery angles.

Figure 2: Scatterplot showing the difference between the measured and predicted peripheral defocus for each intraocular lens at various delivery angles.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×