June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Predominantely hemorragic lesion in nAMD and response to Anti-VEGF treatment
Author Affiliations & Notes
  • Arthur Nassaralla
    Retina, Instituto de Olhos de Goiânia, Goiânia, Goiás, Brazil
  • Miguel Hage Amaro
    Retina, Eye and Laser Institute of Belém, Belém, Pará, Brazil
  • Cristina Muccioli
    Instituto da Visao da Paulista, Sao Paulo, São Paulo, Brazil
  • Teruo Aihara
    Faculdade de Ciencias Medicas da Santa Casa de Sao Paulo, Sao Paulo, São Paulo, Brazil
  • Joao J Nassaralla
    Retina, Instituto de Olhos de Goiânia, Goiânia, Goiás, Brazil
  • Footnotes
    Commercial Relationships   Arthur Nassaralla, None; Miguel Amaro, None; Cristina Muccioli, None; Teruo Aihara, None; Joao Nassaralla, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 3682. doi:
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      Arthur Nassaralla, Miguel Hage Amaro, Cristina Muccioli, Teruo Aihara, Joao J Nassaralla; Predominantely hemorragic lesion in nAMD and response to Anti-VEGF treatment. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3682.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess the prognosis of nAMD with hemorragic choroidal neovascularization treated with ranibizumab, bevacizumab and aflibercept

Methods : We investigated twelve nonconsecutive cases of nAMD with predominantely hemorragic neovascularization over the course of six years. During the investigation, we looked for signs of worsening or improvement in patient’s vision and for difference between the chose drugs results

Results : During the treatment, we found a satisfatory response of the eyes suffering from nAMD with hemorragic choroidal neovascularization when treated with anti VEGF drugs. The first signs of improvement were noticed three months following the initial therapy and the patient who took the longest to show improvement after the begining of the treatment did so after eight months. No patient showed imediate response to the treatment and no difference between the drugs were noticed during the treatment.

Conclusions : These cases of nAMD with hemorragic choroidal neovascularization benefited from the treatment with anti VEGF, despite its first responses being held after three months of treatment. No difference in the result between drugs was noticed. 70% of the eyes treated showed improvement in the visual acuity. Two of the cases evolved to subretinal fibrosis. nAMD is still an important therapy in patients of nAMD

This is a 2021 ARVO Annual Meeting abstract.

 

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