June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Choroidal thickness distribution among different types of CSCR based on multimodal-imaging based classification
Author Affiliations & Notes
  • Sonny Caplash
    Ophthalmology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
  • Supriya Arora
    Princess Margaret Hospital, Nassau, Bahamas
  • Dmitri Maltsev
    Vojnomedicinska akademija, Beograd, Beograd, Serbia
  • Sumit Singh
    Scheie Eye Institute, Philadelphia, Pennsylvania, United States
  • Niroj Kumar Sahoo
    LV Prasad Eye Institute Kode Venkatadri Chowdary Campus, Vijayawada, India
  • Deepika Parameshwarappa
    LV Prasad Eye Institute Kode Venkatadri Chowdary Campus, Vijayawada, India
  • Tarun Arora
    Princess Margaret Hospital, Nassau, Bahamas
  • Alexei Kulikov
    Vojnomedicinska akademija, Beograd, Beograd, Serbia
  • Claudio Iovino
    Eye Clinic, University of Cagliari Department of Surgical Sciences, Italy
  • Filippo Tatti
    Eye Clinic, University of Cagliari Department of Surgical Sciences, Italy
  • Ramkailash Gujar
    Universita degli Studi di Perugia Facolta di Medicina e Chirurgia, Perugia, Umbria, Italy
  • Ramesh S Venkatesh
    Narayana Nethralaya, Bangalore, Karnataka, India
  • Nikitha Reddy
    Narayana Nethralaya, Bangalore, Karnataka, India
  • Ram Snehith
    Narayana Nethralaya, Bangalore, Karnataka, India
  • Enrico Peiretti
    Eye Clinic, University of Cagliari Department of Surgical Sciences, Italy
  • Jay Chhablani
    Ophthalmology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
  • Footnotes
    Commercial Relationships   Sonny Caplash, None; Supriya Arora, None; Dmitri Maltsev, None; Sumit Singh, None; Niroj Sahoo, None; Deepika Parameshwarappa, None; Tarun Arora, None; Alexei Kulikov, None; Claudio Iovino, None; Filippo Tatti, None; Ramkailash Gujar, None; Ramesh Venkatesh, None; Nikitha Reddy, None; Ram Snehith, None; Enrico Peiretti, None; Jay Chhablani, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 655. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Sonny Caplash, Supriya Arora, Dmitri Maltsev, Sumit Singh, Niroj Kumar Sahoo, Deepika Parameshwarappa, Tarun Arora, Alexei Kulikov, Claudio Iovino, Filippo Tatti, Ramkailash Gujar, Ramesh S Venkatesh, Nikitha Reddy, Ram Snehith, Enrico Peiretti, Jay Chhablani; Choroidal thickness distribution among different types of CSCR based on multimodal-imaging based classification. Invest. Ophthalmol. Vis. Sci. 2021;62(8):655.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : We recently reported a multimodal, imaging-based classification classifying Central Serous Chorioretinopathy (CSCR) into simple and complex types depending upon the extent of the disease. In this retrospective, multi-center, observational clinical study, we aimed to investigate subfoveal choroidal thickness (SFCT) among different types of CSCR and its predictive role for treatment outcomes for each subgroup.

Methods : 104 patients with CSCR underwent retrospective chart review focusing on date of initial presentation followed by 3, 6 and 12 month follow-up. Patients were classified into simple or complex CSCR based on a priori clinical criteria and then further classified into primary, recurrent or resolved depending on their clinical course. Various OCT parameters including SFCT, outer retinal atrophy, and central macular thickness (CMT) were evaluated at each visit by masked observers.

Results : Of all studied patients, average age was 52.7 ± 10.6 years with 66.7% being male. The odds ratio of developing recurrent CSCR versus primary CSCR between simple and complex initial presentations was 0.115 (95% CI 0.040-0.350). The mean initial CMT in simple primary was 446.19 ± 136.51 versus 360 ± 48.56 (p <0.05). The mean initial SFCT between simple CSCR and complex CSCR was 384.95 ± 97.48 and 419.05± 106.64 (p<0.10).

Conclusions : Preliminary data suggests that there is prognostic and diagnostic value in SFCT and CMT on initial presentation. The future implication for this project is to use clinically objective data to guide treatment as per a new multimodal classification. Further retrospective chart review is underway to increase statistical power and there is ongoing analysis to investigate the relationship between SFCT and CMT to treatment response.

This is a 2021 ARVO Annual Meeting abstract.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×