Abstract
Purpose :
To evaluate macular microvascular changes following Internal Limiting Membrane (ILM)-peeling surgery for Epiretinal Membrane (ERM) or Macular Hole (MH).
Methods :
A retrospective study, total of 30 patients (30 eyes), 20 patients diagnosed with epiretinal membrane and 10 with macular hole, were evaluated with SS-OCTA after ILM peeling during PPV. Periforveal microvascular change and nonperfusion area were measured by Matlab from the 6mmx6mm and 12mmx12mm SS-OCTA images excluding FAZ and optic discs. The presence of Dissociated Optic Nerve Fiber Layer (DONFL) was evaluated using en-face SS-OCTA images.
Results :
Total of 30 eyes, the best corrected visual acuity after surgery was significantly improved from 0.56 ± 0.36 (logMAR) to 0.32 ± 0.31 (logMAR). In epiretinal membrane, superficial layer nonperfusion area was significantly decreased (p=0.047). In macular hole, the periforveal vessel density in superficial layer after surgery showed a significant decrease (p=0.045), and the deep periforveal vessel density and the deep nonperfusion zone showed a tendency to decrease, but not statistically significant. DONFL was observed in 7 out of 10 patients diagnosed with macular hole, but in 4 out of 20 patients diagnosed with epiretinal membrane. The correlation between periforveal microvascular change and DONFL was not statistically significant.
Conclusions :
Periforveal vessel density after ILM peeling surgery tend to decrease in macular hole and epiretinal membrane. It was observed more significant in macular hole.
This is a 2021 ARVO Annual Meeting abstract.