Abstract
Purpose :
To analyze the type 1 choroidal neovascularization (CNV) patients with central serous chorioretinopathy (CSC) patterns of fundus autofluorescence (FAF) abnormalities
Methods :
This retrospective study included 19 eyes of 19 patients who were diagnosed with type 1 choroidal neovascularization with central serous chorioretinopathy (CSC) patterns of fundus autofluorescence abnormalities and characteristics of pachychoroid spectrum. Fundus autofluorescence patterns with spectral domain optical coherence tomography, best corrected visual acuity, subfoveal choroidal thickness and patterns of intravitreal anti-VEGF injection in type 1 choroidal neovascularization patients were analyzed.
Results :
A total of 19 patients were consisted of 12 males and 7 females. The mean patients age was 68.79±7.55 years and the mean subfoveal choroidal thickness was 301.79±96.35 micron. Central serous chorioretinopathy (CSC) pattern of fundus autofluorescence abnormalities of type 1 choroidal neovascularization patients were grouped as mottled (36.8%), hyper (26.3%), hyper/hypo(36.8%). The mean number of intravitreal anti-VEGF injection per year was significantly lower in the hyper/hypo group than in the hyper group (p=0.046). Also there was a significant positive correlation between the subfoveal choroidal thickness and the interval of loading phase to maintenance phase of intravitreal anti-VEGF injection (r=0.458, p=0.049).
Conclusions :
The central serous chorioretinopathy (CSC) patterns of fundus autofluorescence (FAF) abnormalities in type 1 choroidal neovascularization patients are helpful when predicting the number of intravitreal anti-VEGF injection per year. Additionally the interval of loading phase to maintenance phase of intravitreal anti-VEGF injection can be considering by the subfoveal choroidal thickness of type 1 choroidal neovascularization patients.
This is a 2021 ARVO Annual Meeting abstract.