Abstract
Purpose :
To evaluate long-term clinical outcomes and fundus autofluorescence (FAF) changes in pathents with chronic central serous chorioretinopathy (CSC) according to different FAF patterns.
Methods :
This retrospective study included 22 eyes of 20 patients from 5 years follow-up diagnosed with central serous chorioretinopathy. Best corrected visual acuity, subfoveal choroidal thickness, fundus autofluorescence (FAF) patterns with spectral domain optical coherence tomography, the number of intravitreal anti-VEGF injection and the number of PDT were examined.
Results :
Initial fundus autofluorescence patterns of 22 eyes were grouped as blocked (9, 40.91%), mottled (1, 4.55%), hyper (6, 27.27%), hyper/hypo (5, 22.73%), or descending tract (1, 4.55%). Average onset age was 49.77±8.19. After 5 years, FAF pattern progression showed total 12 eyes (54.55 %), blocked (100.0%), mottled (0.0%), hyper (33.3%), hyper/hypo (20.0%), descending tract (0.0%). Mean fundus hypofluorescence change was 0.42±0.67mm2. Visual prognosis was associated with changes of hyper/hypofluorescence area in fundus autofluorescence image.
Conclusions :
Progression of FAF was observed in eyes with more progressive patterns. Visual prognosis with chronic central serous chorioretinopathy more correlate with hyper/hypoautofluorescence change.
This is a 2021 ARVO Annual Meeting abstract.